Magnetic resonance imaging findings of fatty infiltrate in the cervical flexors in chronic whiplash

Elliott, James M., O'Leary, Shaun, Sterling, Michele, Hendrikz, Joan, Pedler, Ashley and Jull, Gwen (2010) Magnetic resonance imaging findings of fatty infiltrate in the cervical flexors in chronic whiplash. Spine, 35 9: 948-954. doi:10.1097/BRS.0b013e3181bb0e55


Author Elliott, James M.
O'Leary, Shaun
Sterling, Michele
Hendrikz, Joan
Pedler, Ashley
Jull, Gwen
Title Magnetic resonance imaging findings of fatty infiltrate in the cervical flexors in chronic whiplash
Journal name Spine   Check publisher's open access policy
ISSN 0362-2436
1528-1159
Publication date 2010-04-20
Sub-type Article (original research)
DOI 10.1097/BRS.0b013e3181bb0e55
Volume 35
Issue 9
Start page 948
End page 954
Total pages 7
Place of publication Hagerstown, MD, United States
Publisher Lipponcott-Raven
Collection year 2011
Language eng
Subject 0903 Biomedical Engineering
1103 Clinical Sciences
Formatted abstract
Study Design: Retrospective investigation of muscle changes in patients suffering from chronic whiplash-associated disorders (WAD).

Objectives: To quantitatively compare the presence of muscle alterations (fatty infiltrate [MFI] and cross-sectional area [CSA]) in the anterior musculature of the cervical spine in a cohort of chronic whiplash patients (WAD II) and healthy control subjects across muscle and cervical segmental level.

Summary of Background Data: Magnetic resonance imaging can be regarded as the gold standard for muscle imaging. There is little knowledge about in vivo features of anterior neck muscles in patients suffering from chronic WAD and how muscle structure differs across the factors of muscle, vertebral level, age, self-reported pain and disability, body mass index, and duration of symptoms.

Methods: Reliable magnetic resonance imaging measures for MFI and CSA were performed for the anterior cervical muscles bilaterally in 109 female subjects (78 WAD, 31 healthy control; 18-45 years, 3 months to 3 years postinjury). The measures were performed on all subjects for the longus capitis and colli and the sternocleidomastoid muscles.

Results: The WAD subjects had significantly larger MFI and CSA for the anterior muscles compared to healthy control subjects (all P < 0.0001). In addition, the amount of MFI varied by both cervical level and muscle, with the longus capitis/colli having the largest amount of fatty infiltrates at the C2-C3 level (P < 0.0001). MFI was inversely related to age, self-reported pain/disability, and body mass index but directly proportional to duration of symptoms.

Conclusion: There is significantly greater MFI and CSA in the anterior neck muscles, especially in the deeper longus capitis/colli muscles, in subjects with chronic WAD when compared to healthy controls. Future studies are required to investigate the relationships between muscular morphometry and symptoms in patients suffering from acute and chronic WAD.
© 2010, Lippincott Williams & Wilkins.
Keyword MRI
Cervical
Muscle
Fat
Whiplash
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Author prepress title: "MRI findings of fatty infiltrate in the cervical flexors in chronic whiplash".

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 40 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 50 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 16 May 2010, 00:01:01 EST