Facile single step fabrication of microchannels with varying size

Asthana, A., Kim, K.O., Perumal, J., Kim, D.M. and Kim, D.P. (2009) Facile single step fabrication of microchannels with varying size. Lab On a Chip, 9 8: 1138-1142. doi:10.1039/b818987k


Author Asthana, A.
Kim, K.O.
Perumal, J.
Kim, D.M.
Kim, D.P.
Title Facile single step fabrication of microchannels with varying size
Journal name Lab On a Chip   Check publisher's open access policy
ISSN 1473-0197
Publication date 2009
Year available 2009
Sub-type Article (original research)
DOI 10.1039/b818987k
Volume 9
Issue 8
Start page 1138
End page 1142
Total pages 5
Editor Harp Minhas
Place of publication United Kingdom
Publisher Royal Society of Chemistry
Collection year 2010
Language eng
Subject C1
Abstract In this report, we present a non-lithographic embedded template method for rapid and cost-effective fabrication of a monolithic microfluidic device with channels of various sizes. The procedure presented here enables the preparation of microchannels with varying dimensions in a single device without using any sophisticated micromachining instrumentation. In addition, this non-lithographic technique has also been used to fabricate a multilayer-multilevel biopolymer microdevice in a single step. To demonstrate the versatility of the presented method, we have fabricated microfluidic devices with four different materials under different curing/cross linking conditions. We have also demonstrated the application of the fabricated device to generate structured copper alginate microbeads, in vitro protein synthesis in three phase flow, and alternate plugs with liquid spacers.
Keyword MICROFLUIDIC DEVICES
PROTEIN EXPRESSION
DROPLET FORMATION
SYSTEM
MICROFABRICATION
LITHOGRAPHY
ARRAY
PLUGS
PDMS
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 28 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 10 May 2010, 14:30:04 EST by Julie Osborne on behalf of Aust Institute for Bioengineering & Nanotechnology