Isothermal detection of DNA by beacon-assisted detection amplification

Connolly, Ashley R. and Trau, Matt (2010) Isothermal detection of DNA by beacon-assisted detection amplification. Angewandte Chemie (International Edition), 49 15: 2720-2723. doi:10.1002/anie.200906992

Author Connolly, Ashley R.
Trau, Matt
Title Isothermal detection of DNA by beacon-assisted detection amplification
Journal name Angewandte Chemie (International Edition)   Check publisher's open access policy
ISSN 1433-7851
Publication date 2010-04-01
Sub-type Article (original research)
DOI 10.1002/anie.200906992
Volume 49
Issue 15
Start page 2720
End page 2723
Total pages 4
Place of publication Weinheim, Germany
Publisher Wiley-VCH
Collection year 2011
Language eng
Subject 03 Chemical Sciences
06 Biological Sciences
09 Engineering
Formatted abstract
Not bad at all: A simple biological circuit composed of two integrated molecular switches was developed for the detection and amplification of a specific nucleic acid in a biological extract. The nucleic acid is recognized by a molecular beacon, then a DNA polymerase and nicking endonuclease are used to rapidly amplify the signal for sensitive detection of the nucleic acid.
© 2010 Wiley
Keyword Biosensors
DNA detection
DNA nanomachines
Molecular devices
Strand displacement amplification
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Communications

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
Australian Institute for Bioengineering and Nanotechnology Publications
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Citation counts: TR Web of Science Citation Count  Cited 90 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 94 times in Scopus Article | Citations
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Created: Sun, 02 May 2010, 00:09:32 EST