Metabolic engineering of terpenoid biosynthesis in plants

Lücker, Joost, Bouwmeester, Harro J. and Aharoni, Asaph (2007). Metabolic engineering of terpenoid biosynthesis in plants. In R. Verpoorte, A. W. Alfermann and T. S. Johnson (Ed.), Applications of plant metabolic engineering (pp. 219-236) Dordrecht, The Netherlands: Springer. doi:10.1007/978-1-4020-6031-1_9

Author Lücker, Joost
Bouwmeester, Harro J.
Aharoni, Asaph
Title of chapter Metabolic engineering of terpenoid biosynthesis in plants
Title of book Applications of plant metabolic engineering
Place of Publication Dordrecht, The Netherlands
Publisher Springer
Publication Year 2007
Sub-type Other
DOI 10.1007/978-1-4020-6031-1_9
ISBN 9781402060304
Editor R. Verpoorte
A. W. Alfermann
T. S. Johnson
Chapter number 9
Start page 219
End page 236
Total pages 18
Total chapters 14
Language eng
Subjects 0607 Plant Biology
Abstract/Summary Metabolic engineering of terpenoids in plants is a fascinating research topic from two main perspectives. On the one hand, the various biological activities of these compounds make their engineering a new tool for improving a considerable number of traits in crops. These include for example enhanced disease resistance, weed control by producing allelopathic compounds, better pest management, production of medicinal compounds, increased value of ornamentals and fruit and improved pollination. On the other hand, the same plants altered in the profile of terpenoids and their precursor pools make a most important contribution to fundamental studies on terpenoid biosynthesis and its regulation. In this review we describe the recent results with terpenoid engineering, showing that engineering of these compounds and their derivatives in plant cells is feasible, although with some requirements and limitations. For example, in terpenoid engineering experiments crucial factors are the subcellular localization of both the precursor pool and the introduced enzymes, the activity of endogenous plant enzymes which modify the introduced terpenoid skeleton, the costs of engineering in terms of effects on other pathways sharing the same precursor pool and the phytotoxicity of the introduced terpenoids. Finally, we will show that transgenic plants altered in their terpenoid profile exert novel biological activities on their environment, for example influencing insect behavior. Copyright 2007 Springer
Keyword Biosynthesis
Q-Index Code BX

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Created: Fri, 23 Apr 2010, 10:07:43 EST by Ms May Balasaize on behalf of Faculty of Science