Frequency, etiology and treatment of childhood end-stage kidney disease in Australia and New Zealand

Orr, Nigel I.T., McDonald, Stephen P., McTaggart, Steven, Henning, Paul and Craig, Jonathan C. (2009) Frequency, etiology and treatment of childhood end-stage kidney disease in Australia and New Zealand. Paediatric Nephrology, 24 9: 1719-1726. doi:10.1007/s00467-009-1181-2


Author Orr, Nigel I.T.
McDonald, Stephen P.
McTaggart, Steven
Henning, Paul
Craig, Jonathan C.
Title Frequency, etiology and treatment of childhood end-stage kidney disease in Australia and New Zealand
Journal name Paediatric Nephrology   Check publisher's open access policy
ISSN 0931-041X
Publication date 2009
Sub-type Article (original research)
DOI 10.1007/s00467-009-1181-2
Volume 24
Issue 9
Start page 1719
End page 1726
Total pages 8
Editor Dr. O Mehls
Place of publication Germany
Publisher Springer
Collection year 2010
Language eng
Subject C1
920501 Child Health
Formatted abstract
To describe the trends in end-stage kidney disease (ESKD) in children in Australia and New Zealand over time and across different ages, we analyzed data from the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). A total of 1,485 children aged less than 18 years received renal replacement therapy (RRT) during the period from 1963 to 2006, of which children 55.6% were male. The incidence of ESKD increased over the first two decades but has been stable at 8 per million since the mid-1980s. The prevalence of ESKD continues to increase in all age groups, especially among older children, and is currently 50 per million in those aged less than 18 years. The cause of ESKD over the entire cohort was one-third each for glomerulonephritis (32.5%), structural anomalies (hypoplasia/dysplasia, posterior urethral valves or reflux nephropathy, 35.8%), and cystic disease or other conditions (31.7%). Proportionately, glomerulonephritis is becoming less common. Overall, 50% of children were commenced on peritoneal dialysis as the initial RRT modality, 30% were started on hemodialysis, and 20% underwent transplantation pre-emptively. The proportion of children receiving transplants has not increased over time.

Keyword Paediatrics
ANZDATA
Renal Replacement
Epidemiology
Dialysis
Renal Transplantation
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 22 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 22 Apr 2010, 14:33:56 EST by Fiona Mactaggart on behalf of Medicine - Princess Alexandra Hospital