Comparative study of skin sebum and elasticity level in patients with sulfur mustard-induced dermatitis and healthy controls

Davoudi, Seyyed Masoud, Sadr, Bardia, Hayatbakhsh, Mohammad R., Keshavarz, Saeed, Shohrati, Majid, Naghizadeh, Mehdi, Babakoohi, Shahab, Rashighi-Firouzabadi, Mehdi and Firooz, Alireza (2010) Comparative study of skin sebum and elasticity level in patients with sulfur mustard-induced dermatitis and healthy controls. Skin Research and Technology, 16 2: 237-242. doi:10.1111/j.1600-0846.2009.00418.x


Author Davoudi, Seyyed Masoud
Sadr, Bardia
Hayatbakhsh, Mohammad R.
Keshavarz, Saeed
Shohrati, Majid
Naghizadeh, Mehdi
Babakoohi, Shahab
Rashighi-Firouzabadi, Mehdi
Firooz, Alireza
Title Comparative study of skin sebum and elasticity level in patients with sulfur mustard-induced dermatitis and healthy controls
Journal name Skin Research and Technology   Check publisher's open access policy
ISSN 0909-752X
Publication date 2010-05-01
Year available 2009
Sub-type Article (original research)
DOI 10.1111/j.1600-0846.2009.00418.x
Volume 16
Issue 2
Start page 237
End page 242
Total pages 6
Editor Jorgen Serup
Place of publication Denmark
Publisher Wiley-Blackwell Munksgaard
Collection year 2010
Language eng
Subject 920117 Skin and Related Disorders
119999 Medical and Health Sciences not elsewhere classified
Formatted abstract
Background:
Sulfur mustard (SM) - a chemical agent - has both acute and chronic effects on skin. Xerosis, which is deemed to be due to the damage of hydrolipidic barrier of the skin, is the most common complaint of veterans exposed to the chemical. This study was designed to evaluate skin sebum and elasticity in veterans with a history of SM contact.

Methods:
Three hundred and ten subjects were enrolled in this study and were divided into four groups: SM-exposed patients with current skin lesions (n=87); SM-exposed patients without skin lesions (n=71); patients with dermatitis (n=78); and normal controls (n=74). The skin sebum and elasticity were measured in four areas (forehead, suprasternal, palm and back of the hands) using a Sebumeter and a Reviscometer.

Results:
Skin sebum was higher in participants who presented with dermatitis and had history of contact with SM than others; the difference was only statistically significant on the forehead. There was no significant difference in the skin elasticity between the four groups.

Conclusion:
While SM may increase skin sebum in long term, there is no evidence that it has a substantial effect on skin elasticity. © 2009 John Wiley & Sons A/S.
Keyword Dermatitis
Skin elasticity
Skin sebum
Sulfur mustard
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Public Health Publications
 
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Created: Thu, 08 Apr 2010, 21:52:50 EST by Barry Peacock on behalf of School of Public Health