Anxiolytic, hypnotic and sedative medication use in Australia

Hollingworth, SA and Siskind, DJ (2010) Anxiolytic, hypnotic and sedative medication use in Australia. Pharmacoepidemiology and Drug Safety, 19 3: 280-288. doi:10.1002/pds.1899

Author Hollingworth, SA
Siskind, DJ
Title Anxiolytic, hypnotic and sedative medication use in Australia
Journal name Pharmacoepidemiology and Drug Safety   Check publisher's open access policy
ISSN 1053-8569
Publication date 2010-03
Sub-type Article (original research)
DOI 10.1002/pds.1899
Volume 19
Issue 3
Start page 280
End page 288
Total pages 9
Place of publication West Sussex, United Kingdom
Publisher John Wiley and Sons
Collection year 2011
Language eng
Formatted abstract
Purpose New sedative drugs have been marketed in Australia in the last few years.We examined the trends in the prescribing of subsidised
anxiolytic, hypnotic and sedative (AHS) medication use in the Australian population from 2002 to 2007.
Methods We analysed the Medicare Australia and Drug Utilisation Sub-Committee databases for AHS script data from 2002 to 2007 by
source, class of prescriber, gender and 5-year age groups. Scripts were converted to defined daily dose per 1000 population per day (DDD/
1000 population/day) using Australian Bureau of Statistics population data.
Results Overall use of AHS increased from 23.76 to 24.11 DDD/1000 population/day between 2002 and 2007. Anxiolytic medication
utilisation increased as hypnotic medication utilisation decreased. Diazepam was the most widely used anxiolytic followed by alprazolam and
oxazepam. Temazepam was the most widely used hypnotic followed by nitrazepam. Medication use was concentrated in those aged65 years
with peak use in those aged 85–89 years. There was substantial use of anxiolytics in those aged 30–65 years. Age-adjusted utilization was
higher in females than males.
Conclusions The prescribing of AHS medications increased slightly over the last half decade. There is growing use of zolpidem on private
prescription. The gender differences in use reflect the higher prevalence of anxiety and sleep disorders in women. The very high use of these
drugs in elderly people warrants further exploration because of the concomitant increased risks of mortality and morbidity.
Copyright © 2010 John Wiley & Sons, Ltd.
Keyword Anxiolytics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Public Health Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 35 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 40 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 04 Apr 2010, 00:01:50 EST