Molecular genetic markers: discovery, applications, data storage and visualisation

Duran, C., Appleby, N., Edwards, D. and Batley, J (2009) Molecular genetic markers: discovery, applications, data storage and visualisation. Current Bioinformatics, 4 1: 16-27. doi:10.2174/157489309787158198


Author Duran, C.
Appleby, N.
Edwards, D.
Batley, J
Title Molecular genetic markers: discovery, applications, data storage and visualisation
Journal name Current Bioinformatics   Check publisher's open access policy
ISSN 1574-8936
Publication date 2009-01
Year available 2009
Sub-type Article (original research)
DOI 10.2174/157489309787158198
Volume 4
Issue 1
Start page 16
End page 27
Total pages 12
Editor Gupta, S.P.
Place of publication Netherlands
Publisher Bentham Science Publications Ltd.
Collection year 2010
Language eng
Subject C1
829999 Plant Production and Plant Primary Products not elsewhere classified
060102 Bioinformatics
Abstract Molecular genetic markers represent one of the most powerful tools for the analysis of genomes and enable the association of heritable traits with underlying genomic variation. Molecular marker technology has developed rapidly over the last decade and two forms of sequence based marker, Simple Sequence Repeats (SSRs), also known as microsatellites, and Single Nucleotide Polymorphisms (SNPs) now predominate applications in modern genetic analysis. The reducing cost of DNA sequencing has led to the availability of large sequence data sets derived from whole genome sequencing and large scale Expressed Sequence Tag (EST) discovery that enable the mining of SSRs and SNPs, which may then be applied to diversity analysis, genetic trait mapping, association studies, and marker assisted selection. These markers are inexpensive, require minimal labour to produce and can frequently be associated with annotated genes. Here we review automated methods for the discovery of SSRs and SNPs and provide an overview of the diverse applications of these markers.
Keyword simple sequence repeats (SSRs)
Single Nucleotide Polymorphisms (snps)
Molecular Markers
Expressed Sequence Tags (ESTs)
genome sequencing
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Agriculture and Food Sciences
 
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Created: Thu, 01 Apr 2010, 08:04:11 EST by Kaye Hunt on behalf of School of Land, Crop and Food Sciences