Enhanced invasion of blood group A1 erythrocytes by Plasmodium falciparum

Chung, Wendy Y., Gardiner, Donald L., Hyland, Catherine, Gatton, Michelle, Kemp, David J. and Trenholme, Katharine R. (2005) Enhanced invasion of blood group A1 erythrocytes by Plasmodium falciparum. Molecular and Biochemical Parasitology, 144 1: 128-130. doi:10.1016/j.molbiopara.2005.08.004

Author Chung, Wendy Y.
Gardiner, Donald L.
Hyland, Catherine
Gatton, Michelle
Kemp, David J.
Trenholme, Katharine R.
Title Enhanced invasion of blood group A1 erythrocytes by Plasmodium falciparum
Journal name Molecular and Biochemical Parasitology   Check publisher's open access policy
ISSN 0166-6851
Publication date 2005-11
Sub-type Article (original research)
DOI 10.1016/j.molbiopara.2005.08.004
Volume 144
Issue 1
Start page 128
End page 130
Total pages 3
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Subject 06 Biological Sciences
11 Medical and Health Sciences
Abstract Invasion of the malaria parasite Plasmodium falciparum into human erythrocytes is a highly complex multi-step procedure. It involves parasite ligands on the merozoite interacting with receptors on the erythrocyte surface. P. falciparum is able to exploit multiple receptor ligand interactions to achieve invasion and to date, several erythrocyte surface receptors have already been identified [1]. However, several as yet unidentified receptors on the erythrocyte surface have also been postulated to play a role in invasion and the specific molecular interactions between merozoite surface ligands and erythrocyte receptors remain elusive. Inhibition of RBC invasion would prevent infection and consequently disease, therefore considerable effort has gone into identification and characterization of molecules involved in this process.
Keyword Plasmodium falciparum
Erythrocyte invasion
ABO blood groups
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 31 Mar 2010, 15:47:00 EST by Therese Egan on behalf of Faculty Of Health Sciences