Rheumatoid arthritis association at 6q23

Thompson, Wendy, Wellcome Trust Case Control Consortium, Brown, Matthew A., Bradbury, Linda A. and et al. (2007) Rheumatoid arthritis association at 6q23. Nature Genetics, 39 12: 1431-1433. doi:10.1038/ng.2007.32


Author Thompson, Wendy
Wellcome Trust Case Control Consortium
Brown, Matthew A.
Bradbury, Linda A.
et al.
Title Rheumatoid arthritis association at 6q23
Journal name Nature Genetics   Check publisher's open access policy
ISSN 1061-4036
1546-1718
Publication date 2007-12
Sub-type Article (original research)
DOI 10.1038/ng.2007.32
Volume 39
Issue 12
Start page 1431
End page 1433
Total pages 3
Editor Myles Axton
Place of publication New York, U.S.A.
Publisher Nature America Inc.
Language eng
Subject 1103 Clinical Sciences
Formatted abstract
The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10-5-5 x 10-7 in a genome-wide association screen. One, rs6920220, was unequivocally replicated ( trend P = 1.1 x 10-8) in a validation study, as described here. This SNP maps to 6q23, between the genes oligodendrocyte lineage transcription factor 3 (OLIG3) and tumor necrosis factor-alpha-induced protein 3 ( TNFAIP3).
© 2007 Nature Publishing Group.

Keyword Nf-kappa-b
Population
Responses
PTPN22
Rise
Gene
A20
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
ERA 2012 Admin Only
UQ Diamantina Institute Publications
 
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Created: Wed, 31 Mar 2010, 12:17:39 EST by June Temby on behalf of UQ Diamantina Institute