PCOT2: Principal Coordinates and Hotelling’s T^2 for the analysis of microarray data

Song, Sarah and Black, Michael (2007). PCOT2: Principal Coordinates and Hotelling’s T^2 for the analysis of microarray data. , .


Author Song, Sarah
Black, Michael
Title PCOT2: Principal Coordinates and Hotelling’s T^2 for the analysis of microarray data
Formatted title
PCOT2: Principal Coordinates and Hotelling’s T2 for the analysis of microarray data
Publication date 2007-04-25
Publisher Bioconductor
Editor Gentleman Robert
Total pages 8
Language eng
Subject 0104 Statistics
0604 Genetics
970101 Expanding Knowledge in the Mathematical Sciences
92 Health
970110 Expanding Knowledge in Technology
Abstract/Summary pcot2 is an R-package for the analysis of groups of genes in microarray experiments. It utilizes inter-gene correlation information to detect significant alterations in the activities of gene sets. Incorporating additional (usually functional) information into the data analysis process allows gene interactions to be investigated in a statistical framework. One of the reasons that gene set analysis is becoming important is that it is suitable for detecting small coordinated changes in expression of groups of genes which are functionally related, which may not be considered significant in a single gene analysis. This vignette gives a tutorial-style introduction to the functions in the pcot2 package. These functions are used for testing and visualizing changes in expression activity for groups of genes.

Document type: Working Paper
Collection: School of Nursing, Midwifery and Social Work Publications
 
Versions
Version Filter Type
Citation counts: Google Scholar Search Google Scholar
Created: Sun, 28 Mar 2010, 17:11:56 EST by Dr Sarah Song on behalf of School of Nursing, Midwifery and Social Work