Similar prevalence of hyperaldosteronism in African American and white subjects with resistant hypertension

Husain, Saima, Nishizaka, Marie K., Pratt-Ubunama, Monique N., Oparil, Suzanne, Gaddam, Krishna K., Pimenta, Eduardo and Calhoun, David A. (2008). Similar prevalence of hyperaldosteronism in African American and white subjects with resistant hypertension. In: Abstracts of the American Society of Hypertension 23rd Annual Scientific Meeting. American Society of Hypertension (ASH) 23nd Annual Scientific Meeting and Exposition, New Orleans, LA., U.S., (P-385-P-385). 14-17 May 2008.

Author Husain, Saima
Nishizaka, Marie K.
Pratt-Ubunama, Monique N.
Oparil, Suzanne
Gaddam, Krishna K.
Pimenta, Eduardo
Calhoun, David A.
Title of paper Similar prevalence of hyperaldosteronism in African American and white subjects with resistant hypertension
Conference name American Society of Hypertension (ASH) 23nd Annual Scientific Meeting and Exposition
Conference location New Orleans, LA., U.S.
Conference dates 14-17 May 2008
Proceedings title Abstracts of the American Society of Hypertension 23rd Annual Scientific Meeting   Check publisher's open access policy
Journal name Journal of Clinical Hypertension   Check publisher's open access policy
Place of Publication Hoboken, NJ, United States
Publisher Le Jacq Communications
Publication Year 2008
Sub-type Poster
Open Access Status
ISSN 1524-6175
1751-7176
Volume 10
Issue 5 Supp. A
Start page P-385
End page P-385
Total pages 1
Language eng
Abstract/Summary Purpose of the study was to test for racial differences in the prevalence of hyperaldosteronism in subjects with resistant hypertension. Consecutive subjects referred to the University of Alabama at Birmingham (UAB) hypertension clinic for resistant hypertension (uncontrolled blood pressure on 3 antihypertensive agents) were prospectively evaluated with a plasma aldosterone concentration (PAC), plasma renin activity (PRA), a 24-hr urine collection for aldosterone, cortisol, sodium and potassium during a normal diet. All subjects were on a stable antihypertensive regimen without use of potassium sparing diuretics. For results see the table. The prevalence of hyperaldosteronism on the basis of ARR 20 (29.6% vs. 31.1%) or using PRA<1.0 and urinary aldosterone 12g/24- hr (23.7% Vs 22.6 %) was not different by race. These data demonstrate that there is no racial difference in the prevalence of hyperaldosteronism in subjects with resistant hypertension. These findings support equal vigor in screening African American and white patients with resistant hypertension for primary aldosteronism.
Subjects 1101 Medical Biochemistry and Metabolomics
1102 Cardiovascular Medicine and Haematology
1103 Clinical Sciences
Keyword Hypertension
Hyperaldosteronism
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes Poster: Secondary Hypertension

 
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Created: Tue, 23 Mar 2010, 09:22:17 EST by Therese Egan on behalf of Faculty Of Health Sciences