The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer

McArdle, P. A., Canna, K., McMillan, D. C., McNicol, A-M., Campbell, R. and Underwood, M. A. (2004) The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer. British Journal of Cancer, 91 3: 541-543. doi:10.1038/sj.bjc.6601943


Author McArdle, P. A.
Canna, K.
McMillan, D. C.
McNicol, A-M.
Campbell, R.
Underwood, M. A.
Title The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
Journal name British Journal of Cancer   Check publisher's open access policy
ISSN 0007-0920
1532-1827
Publication date 2004-07
Sub-type Article (original research)
DOI 10.1038/sj.bjc.6601943
Open Access Status DOI
Volume 91
Issue 3
Start page 541
End page 543
Total pages 3
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Abstract The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27–4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25–4.22, P=0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer.
Keyword CD4+
CD8+
T-lymphocytes
survival
prostate cancer
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Tue, 16 Mar 2010, 16:27:46 EST by Laura McTaggart on behalf of Faculty Of Health Sciences