Nanogoldpharmaceutics: Evaluating the response of experimentally-induced polyarthritis in rat models to colloidal gold

Brown, Christopher L., Bushell, Gillian R., Tiekink, Edward R. T. and Whitehouse, Michael W . (2008). Nanogoldpharmaceutics: Evaluating the response of experimentally-induced polyarthritis in rat models to colloidal gold. In: Philippe Collery, Ivan Maymard, Theophile Theophanides, Lylia Khassanova and Thomas Collery, Proceedings of the 10th International Symposium on Metal Ions in Biology and Medicine. 10th International Symposium on Metal Ions in Biology and Medicine (10th ISMIBM), Bastia, Corsica, France, (556-560). 19-22 May 2008.

Author Brown, Christopher L.
Bushell, Gillian R.
Tiekink, Edward R. T.
Whitehouse, Michael W .
Title of paper Nanogoldpharmaceutics: Evaluating the response of experimentally-induced polyarthritis in rat models to colloidal gold
Conference name 10th International Symposium on Metal Ions in Biology and Medicine (10th ISMIBM)
Conference location Bastia, Corsica, France
Conference dates 19-22 May 2008
Proceedings title Proceedings of the 10th International Symposium on Metal Ions in Biology and Medicine   Check publisher's open access policy
Journal name Metal Ions: Metal Ions in Biology and Medicine. Les ions métalliques en biologie et en médecine   Check publisher's open access policy
Place of Publication Montrouge, France
Publisher John Libbey Eurotext
Publication Year 2008
Sub-type Fully published paper
ISBN 9782742007141
2742007148
ISSN 1257-2535
Editor Philippe Collery
Ivan Maymard
Theophile Theophanides
Lylia Khassanova
Thomas Collery
Volume 10
Start page 556
End page 560
Total pages 5
Language eng
Formatted Abstract/Summary
Nanosized gold particles (27 +/- 3 nm) in the form of Tyndall's purple are demonstrated to be effective in ameliorating the symptoms of mycobacterial-, collagen- and pristane-induced polyarthritis in two rat models. This contrasts the clinically used drug sodium aurothiomalate that was only effective against mycobacterial-induced arthritis but not to the same extent as Au0.
Subjects 1115 Pharmacology and Pharmaceutical Sciences
0304 Medicinal and Biomolecular Chemistry
Keyword Nanogoldpharmaceutics
Polyarthritis
Colloidal gold
Gold
Aurothiomalate
Nanoparticle
Experimental arthritis
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Presented during the Session "Inflammation and immunity (Part I)". Published in Part XI: "Inflammation and immunity".

 
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Created: Mon, 15 Mar 2010, 14:07:06 EST by Michael Affleck on behalf of School of Medicine