Acompanhamento da funcao renal na fase aguda do infarto do miocardio como fator prognostico na evolucao intra-hospitalar e em 1 ano de seguimento (Renal function development during the acute phase of myocardial infarction as a prognostic factor in in-hospital and one year outcomes)

Pimenta, Eduardo, Ramos, Rui Fernando, Gun, Carlos, dos Santos, Elizabete Silva, Timerman, Ari and Piegas, Leopoldo Soares (2004). Acompanhamento da funcao renal na fase aguda do infarto do miocardio como fator prognostico na evolucao intra-hospitalar e em 1 ano de seguimento (Renal function development during the acute phase of myocardial infarction as a prognostic factor in in-hospital and one year outcomes). In: Arquivos Brasileiros de Cardiologia. Proceedings of: LIX Congresso da Sociedade Brasileira de Cardiologia. 59º Congresso da Sociedade Brasileira de Cardiologia (SBC), Rio de Janeiro, Brazil, (). 26-29 September 2004.


Author Pimenta, Eduardo
Ramos, Rui Fernando
Gun, Carlos
dos Santos, Elizabete Silva
Timerman, Ari
Piegas, Leopoldo Soares
Title of paper Acompanhamento da funcao renal na fase aguda do infarto do miocardio como fator prognostico na evolucao intra-hospitalar e em 1 ano de seguimento (Renal function development during the acute phase of myocardial infarction as a prognostic factor in in-hospital and one year outcomes)
Formatted title Acompanhamento da função renal na fase aguda do infarto do miocárdio como fator prognóstico na evolução intra-hospitalar e em 1 ano de seguimento (Renal function development during the acute phase of myocardial infarction as a prognostic factor in in-hospital and one year outcomes)
Conference name 59º Congresso da Sociedade Brasileira de Cardiologia (SBC)
Conference location Rio de Janeiro, Brazil
Conference dates 26-29 September 2004
Proceedings title Arquivos Brasileiros de Cardiologia. Proceedings of: LIX Congresso da Sociedade Brasileira de Cardiologia   Check publisher's open access policy
Place of Publication São Paulo, Brasil
Publisher Sociedade Brasileira de Cardiologia
Publication Year 2004
Sub-type Oral presentation
ISSN 0066-782X
1678-4170
Volume 83
Issue Supp. 3
Language por
Formatted Abstract/Summary Objective
To analyze the role of renal dysfunction at admission or during hospitalization in patients with acute myocardial infarction (AMI).

Methods
Two hundred and seventy-four patients with AMI were assessed between January 2000 and December 2001. Renal function was monitored by serum creatinine (Cr) measurement at admission and peak level during hospitalization. Creatinine clearance (CrCl) was estimated by the Cockcroft-Gault formula. In-hospital and one-year morbidity and mortality were evaluated.

Results
Mean age of the population studied was 62.2 ± 13.5, and 73% of the patients were male. Renal function was more reduced in male patients and in those with systemic arterial hypertension and prior CABG. Multivariate analysis showed higher hospital mortality rates associated with increased peak serum Cr levels (OR: 1.18 95% CI:1.18-2.77 p = 0.006), decreased baseline CrCl (OR:0.96 95% CI:0.93-0.99 p = 0.025) and peak CrCl (OR:0.96 95% CI:0.92-0.99 p = 0.023). Percent difference between baseline CrCl and the lowest CrCl obtained during hospitalization also indicated higher mortality rates (OR: 1.04 95% CI: 1.00-1.07 p = 0.033). No change was observed in the one-year morbidity and mortality from worsening of renal function.

Conclusion
Renal dysfunction at admission and its deterioration during hospitalization have proved to be a major prognostic marker for immediate poor outcome.
Subjects 1102 Cardiovascular Medicine and Haematology
Keyword Acute myocardial infarction
Renal insufficiency
Cardiovascular diseases
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes Presented as Session TLO 531 during "Fatores prognósticos nas síndromes coronarianas agudas" (Prognostic factors in acute coronary syndromes). Abstract from later English version of the paper.

 
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