Predictors of short and long term outcome in patellofemoral pain syndrome: A prospective longitudinal study

Collins, Natalie J., Crossley, Kay M., Darnell, Ross and Vicenzino, Bill (2010) Predictors of short and long term outcome in patellofemoral pain syndrome: A prospective longitudinal study. BMC Musculoskeletal Disorders, 11 11-1-11-7. doi:10.1186/1471-2474-11-11

Author Collins, Natalie J.
Crossley, Kay M.
Darnell, Ross
Vicenzino, Bill
Title Predictors of short and long term outcome in patellofemoral pain syndrome: A prospective longitudinal study
Journal name BMC Musculoskeletal Disorders   Check publisher's open access policy
ISSN 1471-2474
Publication date 2010-01-19
Sub-type Article (original research)
DOI 10.1186/1471-2474-11-11
Open Access Status DOI
Volume 11
Start page 11-1
End page 11-7
Total pages 7
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2011
Language eng
Formatted abstract
Background: Patellofemoral pain syndrome (PFP) is a common musculoskeletal condition that has a tendency to
become chronic and problematic in a proportion of affected individuals. The objective of this study was to identify
prognostic factors that may have clinical utility in predicting poor outcome on measures of pain and function in
individuals with PFP.
Methods: A prospective follow-up study was conducted of 179 participants in a randomised clinical trial. Nine
baseline factors (age, gender, body mass index, arch height, duration of knee pain, worst pain visual analogue
scale, Kujala Patellofemoral Score (KPS), functional index questionnaire (FIQ), step down repetitions) were
investigated for their prognostic ability on outcome assessed at six, 12 and 52 weeks (worst pain, KPS and FIQ).
Factors with significant univariate associations were entered into multivariate linear regression models to identify a
group of factors independently associated with poor outcome.
Results: Long symptom duration was the most consistent predictor of poor outcome over 52 weeks rated on the
KPS and the FIQ (β-0.07, 95% confidence interval -0.1 to -0.03, p < 0.000; and -0.02, -0.03 to -0.01, p < 0.000,
respectively). Worse KPS at baseline was predictive of outcome at six, 12 and 52 weeks. Gender, body mass index
and arch height were generally not associated with outcome (univariate analysis), while age, worst pain, FIQ and
step downs were excluded during multivariate analyses.
Conclusions: Patients presenting with PFP of long duration who score worse on the KPS have a poorer prognosis,
irrespective of age, gender and morphometry. These results suggest that strategies aimed at preventing chronicity
of more severe PFP may optimise prognosis.
© 2010 Collins et al; licensee BioMed Central Ltd.
Keyword Anterior knee pain
Prospective follow-up
Randomized clinical-trial
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article# 11, pp.1-7

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Health and Rehabilitation Sciences Publications
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Created: Sun, 07 Mar 2010, 00:07:05 EST