Permethrin and ivermectin for scabies

Currie, Bart J. and McCarthy, James S. (2010) Permethrin and ivermectin for scabies. New England Journal of Medicine, 362 8: 717-725. doi:10.1056/NEJMct0910329

Author Currie, Bart J.
McCarthy, James S.
Title Permethrin and ivermectin for scabies
Journal name New England Journal of Medicine   Check publisher's open access policy
ISSN 0028-4793
Publication date 2010-02-25
Sub-type Article (original research)
DOI 10.1056/NEJMct0910329
Volume 362
Issue 8
Start page 717
End page 725
Total pages 9
Place of publication Boston, United States
Publisher Massachusetts Medical Society
Collection year 2011
Language eng
Formatted abstract
In a remote aboriginal community in tropical northern Australia, a mother comes to the health center with her 4-year-old son, who has multiple sores on the skin of his arms and legs. He is treated with a single dose of intramuscular penicillin G benzathine and with the application of topical 5% permethrin cream over his whole body. A week later, the pyoderma has substantially resolved, but the boy continues to scratch his hands and feet. The clinic nurse visits the family house and finds that skin sores are present on both infants who live in the household, three of the six young children, and one of the three adolescents. Some also have scratches and small interdigital excoriations, which are consistent with scabies. An infirm elderly aunt living in the house is found to have widespread areas of extensively crusted and scaly skin, which are especially prominent on her hands, elbows, armpits, knees, and buttocks. All the household members are given topical permethrin, and the aunt is referred to the hospital for oral ivermectin therapy.
Copyright © 2010 Massachusetts Medical Society.
Keyword Sarcoptes-scabiei
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors’ clinical recommendations.'

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 81 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 07 Mar 2010, 00:01:46 EST