Biologically active compounds with with anti-angiogenic properties

Becker, Bernd, Condie, Glenn, Halliday, Judy, McKeveney, Declan, Meutermans, Wim, Muldoon, Craig, Premraj, Rajaratnam, Ramsdale, Tracie Elizabeth, Tometzki, Gerald and Zuegg, Johannes (2005). Biologically active compounds with with anti-angiogenic properties. WO/2005/097142; PCT/AU2005/000506.

Creator Becker, Bernd
Condie, Glenn
Halliday, Judy
McKeveney, Declan
Meutermans, Wim
Muldoon, Craig
Premraj, Rajaratnam
Ramsdale, Tracie Elizabeth
Tometzki, Gerald
Zuegg, Johannes
Patent title Biologically active compounds with with anti-angiogenic properties
Date of issue 2005-10-20
Patent owner Alchemia Limited
Patent number WO/2005/097142; PCT/AU2005/000506
Country of origin Australia
Language eng
Subjects 1101 Medical Biochemistry and Metabolomics
Abstract/Summary A method for inhibiting angiogenesis in a subject comprising administering to the subject at least one compound of General Formula (I), wherein the ring or any chiral center(s) may be of any configuration; Z is sulphur, oxygen, CH2, C(O), C(O)HN, NH, NRA or hydrogen, in the case where Z is hydrogen then R1 is not present, RA is selected from the set defined for R1 to R5, X and X' are independently oxygen or nitrogen providing that at least one X of General Formula (I) is nitrogen, X or X' may also combine independently with one of R1 to R5 to form an azide, R1 to R5 are independently selected from the following definition which includes but is not limited to H or an alkyl, acyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl substituent of 1 to 20 atoms, which is optionally substituted, and can be branched or linear, and R6 and R7 are hydrogen, or may combine to form a carbonyl function.
Keyword Glucosamine
Biologically active compounds

Document type: Patent
Collection: Institute for Molecular Bioscience - Publications
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Created: Wed, 24 Feb 2010, 09:10:35 EST by Macushla Boyle on behalf of Institute for Molecular Bioscience