Synthesis and surface modification of birefringent vaterite microspheres

Vogel, Robert, Persson, Martin, Feng, Chao, Parkin, Simon J., Nieminen, Timo A., Wood, Barry, Heckenberg, Norman R. and Rubinsztein-Dunlop, Halina (2009) Synthesis and surface modification of birefringent vaterite microspheres. Langmuir, 25 19: 11672-11679. doi:10.1021/la901532x


Author Vogel, Robert
Persson, Martin
Feng, Chao
Parkin, Simon J.
Nieminen, Timo A.
Wood, Barry
Heckenberg, Norman R.
Rubinsztein-Dunlop, Halina
Title Synthesis and surface modification of birefringent vaterite microspheres
Journal name Langmuir   Check publisher's open access policy
ISSN 0743-7463
Publication date 2009-09-03
Year available 2009
Sub-type Article (original research)
DOI 10.1021/la901532x
Volume 25
Issue 19
Start page 11672
End page 11679
Total pages 8
Editor David G. Whitten
Josef F. Holzwarth
Ralph G. Nuzzo
Richard Crooks
Place of publication United States of America
Publisher American Chemical Society,
Collection year 2010
Language eng
Subject C1
970102 Expanding Knowledge in the Physical Sciences
0205 Optical Physics
Abstract This paper reports on the synthesis of birefringent vaterite microspheres with narrow size distribution using a seeded growth method. In a post-treatment the microspheres were stabilized and functionalized through coating with a combination of organosilica and silica. The coating vastly enhanced the stability of the vaterite microspheres in biological buffers and allowed the attachment of biomolecules such as DNA or proteins. As an example, streptavidin was attached to the surface of the functionalized microspheres. These results pave the way for the use of birefringent vaterite particles for the micromanipulation of single biological molecules such as DNA or specific proteins in an optical trap capable of exerting and measuring torques. The stabilized birefringent microspheres may also find use for biosensor and biological screening applications.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
2010 Higher Education Research Data Collection
 
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Created: Tue, 23 Feb 2010, 14:56:33 EST by Jo Hughes on behalf of Physics