Suicide attempt in first-episode psychosis: A 7.4 year follow-up study

Robinson, J, Harris, MG, Harrigan, SM, Henry, LP, Farrelly, S, Prosser, A, Schwartz, O, Jackson, H and McGorry, PD (2010) Suicide attempt in first-episode psychosis: A 7.4 year follow-up study. Schizophrenia Research, 116 1: 1-8. doi:10.1016/j.schres.2009.10.009

Author Robinson, J
Harris, MG
Harrigan, SM
Henry, LP
Farrelly, S
Prosser, A
Schwartz, O
Jackson, H
McGorry, PD
Title Suicide attempt in first-episode psychosis: A 7.4 year follow-up study
Journal name Schizophrenia Research   Check publisher's open access policy
ISSN 0920-9964
Publication date 2010-01
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.schres.2009.10.009
Volume 116
Issue 1
Start page 1
End page 8
Total pages 8
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Collection year 2011
Language eng
Formatted abstract
Individuals with first-episode psychosis demonstrate high rates of suicide attempt (SA). Aims: 1) To examine the prevalence of, and risk factors for, SA in a first-episode psychosis (FEP) cohort over a 7.4 year follow-up period. 2) To investigate differences between single versus multiple suicide attempters.
This study reports baseline and follow-up data from a naturalistic, prospective follow-up of 413 FEP patients treated at a specialist early psychosis centre. Assessments were conducted at treatment entry, initial symptom remission or stabilization, and long term follow-up. Binary logistic regression models were used to assess unadjusted and adjusted associations between early illness and sociodemographic characteristics and two outcome measures: any SA during follow-up; and multiple SAs.
Follow-up data were available for 282 participants. Sixty-one (21.6%) made a suicide attempt over the follow-up period, including 12 successful suicides. The following baseline risk factors increased the risk of any SA: history of self-harm (OR = 4.27; p < 0.001), suicidal tendencies (OR = 2.30; p = 0.022), being depressed for > 50% of the initial psychotic episode (OR = 2.49; p = 0.045), and hopelessness (OR = 2.03; p = 0.030). History of problem alcohol use increased the risk of multiple SAs (OR = 4.43; 95% CI (1.05-18.7); p = 0.043).
The prevalence of suicide attempt in this study exceeds reports from short-term FEP studies but is comparable to longer term follow-up studies, indicating that risk remains elevated for at least 7 years following commencement of treatment. The key predictor of future suicide attempt was previous self-harm, indicating that interventions for self-harm are required. © 2009 Elsevier B.V. All rights reserved.
Keyword First-episode psychosis
Suicide attempt
Park Multidiagnostic Instrument
Randomized Controlled-trial
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 27 October 2009.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Public Health Publications
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Created: Sun, 14 Feb 2010, 00:00:34 EST