DSB proteins and bacterial pathogenicity

Heras, B, Shouldice, S. R., Totsika, M, Scanlon, M. J., Schembri, M. A. and Martin, J. L. (2009) DSB proteins and bacterial pathogenicity. Nature Reviews Microbiology, 7 3: 215-225. doi:10.1038/nrmicro2087

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Author Heras, B
Shouldice, S. R.
Totsika, M
Scanlon, M. J.
Schembri, M. A.
Martin, J. L.
Title DSB proteins and bacterial pathogenicity
Journal name Nature Reviews Microbiology   Check publisher's open access policy
ISSN 1740-1526
Publication date 2009-03
Sub-type Article (original research)
DOI 10.1038/nrmicro2087
Open Access Status
Volume 7
Issue 3
Start page 215
End page 225
Total pages 11
Editor Susan Jones
Place of publication London England U.K.
Publisher Nature Publishing Group
Collection year 2010
Language eng
Subject C1
9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
920109 Infectious Diseases
0605 Microbiology
060502 Infectious Agents
0601 Biochemistry and Cell Biology
060102 Bioinformatics
060107 Enzymes
Abstract If DNA is the information of life, then proteins are the machines of life — but they must be assembled and correctly folded to function. A key step in the protein-folding pathway is the introduction of disulphide bonds between cysteine residues in a process called oxidative protein folding. Many bacteria use an oxidative protein-folding machinery to assemble proteins that are essential for cell integrity and to produce virulence factors. Although our current knowledge of this machinery stems largely from Escherichia coli K-12, this view must now be adjusted to encompass the wider range of disulphide catalytic systems present in bacteria.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
Institute for Molecular Bioscience - Publications
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Citation counts: TR Web of Science Citation Count  Cited 130 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 129 times in Scopus Article | Citations
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Created: Fri, 12 Feb 2010, 11:33:00 EST by Susan Allen on behalf of Institute for Molecular Bioscience