The molecular epidemiology of extended-spectrum beta-lactamase producing organisms

Paterson, David L. (2008) The molecular epidemiology of extended-spectrum beta-lactamase producing organisms. Enfermedades Infecciosas y Microbiología Clínica, 26 7: 403-403. doi:10.1157/13125635


Author Paterson, David L.
Title The molecular epidemiology of extended-spectrum beta-lactamase producing organisms
Journal name Enfermedades Infecciosas y Microbiología Clínica   Check publisher's open access policy
ISSN 0213-005X
Publication date 2008-09
Year available 2008
Sub-type Article (original research)
DOI 10.1157/13125635
Volume 26
Issue 7
Start page 403
End page 403
Total pages 1
Place of publication Spain
Publisher Elsevier Doyma
Language eng
Subject 110309 Infectious Diseases
1115 Pharmacology and Pharmaceutical Sciences
1117 Public Health and Health Services
Abstract Extended-spectrum beta-lactamase (ESBL) producing organisms have fascinated scientists and frustrated clinicians and microbiologists for more than 20 years. Much insight has been gained with respect to the beta-lactamases themselves. In many cases their crystal structure has been deduced and tremendous insights have been gained into the structure-function relationships of these enzymes. Yet, from a clinical perspective, we may still see outbreaks of infection within hospitals or other healthcare facilities. As is widely reported, there are also significant issues with respect to acquisition of ESBL-producing organisms in the community. This is a tremendously important problem from a global perspective as it threatens use of many common antibiotics when patients present from the community to the emergency department.
Keyword beta-lactamase
ESBL
Infection
Hospitals
Healthcare facilities
Antibiotics
Q-Index Code CX
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
UQ Centre for Clinical Research Publications
 
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Created: Fri, 22 Jan 2010, 10:06:06 EST by Macushla Boyle on behalf of Royal Brisbane Clinical School