Rotavirus hospitalisation in New Zealand children under 3 years of age

Grimwood, Keith, Huang, Q. Sue, Cohet, Catheine, Gosling, Isobelle A., Hook, Sarah M., Teele, David W., Pinnock, Ralph E., Nicholson, William R., Graham, David A., Farrell, Alan P., Leadbitter, Philip and Lennon, Diana R. (2006) Rotavirus hospitalisation in New Zealand children under 3 years of age. Journal of Paediatrics and Child Health, 42 4: 196-203. doi:10.1111/j.1440-1754.2006.00829.x

Author Grimwood, Keith
Huang, Q. Sue
Cohet, Catheine
Gosling, Isobelle A.
Hook, Sarah M.
Teele, David W.
Pinnock, Ralph E.
Nicholson, William R.
Graham, David A.
Farrell, Alan P.
Leadbitter, Philip
Lennon, Diana R.
Title Rotavirus hospitalisation in New Zealand children under 3 years of age
Journal name Journal of Paediatrics and Child Health   Check publisher's open access policy
ISSN 1034-4810
Publication date 2006-04
Year available 2006
Sub-type Article (original research)
DOI 10.1111/j.1440-1754.2006.00829.x
Volume 42
Issue 4
Start page 196
End page 203
Total pages 8
Place of publication Melbourne, Australia
Publisher Blackwell Scientific
Language eng
Subject 1114 Paediatrics and Reproductive Medicine
111403 Paediatrics
Abstract Objective: To describe the epidemiology of severe rotavirus gastroenteritis and to estimate the hospitalisation rates of this illness in New Zealand children under 3 years of age. Methods: Children under 3 years of age with acute diarrhoea admitted to 1 of 8 study hospitals between 1 May 1998 and 30 April 2000 were surveyed. Their socio-demographic, treatment and length-of-stay data were recorded and stool samples tested by a rotavirus-specific enzyme-linked immunoassay. National hospital discharge data for infectious diarrhoea (International Classification of Diseases, ninth revision, 003–009) were reviewed, allowing population-based estimates for rotavirus-related hospitalisation in New Zealand. Results: Of 2019 enrolled children, 1138 (56.4%) provided stools for testing, and of these 485 (42.6%) tested rotavirus positive. Rotavirus detection varied significantly by age (26.8% for 0 to 5 months, 42.5% for 6 to 11 months and 52.1% for children aged 12 to 35 months; P < 0.001), and by season (51.2% in winter/spring vs. 24.5% in summer/autumn; P < 0.001). While those infected with rotavirus were more likely to be dehydrated (50.6% vs. 37.4%; P < 0.001), their median hospital stay was similar (1.0 vs. 2.0 days; P = 0.09) to other children with acute gastroenteritis. The estimated national hospitalisation rate for rotavirus diarrhoea in children under 3 years, standardised for age and season, was 634 (95% CI 597, 672) per 100 000. In New Zealand, rotaviruses result in 1 in 52 children being hospitalised by 3 years of age. Conclusions: Rotavirus diarrhoea is an important, potentially vaccine-preventable cause of hospitalisation in New Zealand children, especially during winter and spring seasons.
Keyword Child
New Zealand
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Created: Thu, 21 Jan 2010, 09:26:06 EST by Macushla Boyle on behalf of Royal Brisbane Clinical School