Depression and suicidal ideation after predictive testing for Huntington's Disease: A two-year follow-up study

Larsson, Maria U., Luszcz, Mary A., Bui, The-Hung and Robins Wahlin, Tarja-Brita (2006) Depression and suicidal ideation after predictive testing for Huntington's Disease: A two-year follow-up study. Journal of Genetic Counseling, 15 5: 361-374. doi:10.1007/s10897-006-9027-6


Author Larsson, Maria U.
Luszcz, Mary A.
Bui, The-Hung
Robins Wahlin, Tarja-Brita
Title Depression and suicidal ideation after predictive testing for Huntington's Disease: A two-year follow-up study
Journal name Journal of Genetic Counseling   Check publisher's open access policy
ISSN 1059-7700
1573-3599
Publication date 2006-10
Sub-type Article (original research)
DOI 10.1007/s10897-006-9027-6
Volume 15
Issue 5
Start page 361
End page 374
Total pages 14
Place of publication New York, United States
Publisher Springer New York
Language eng
Subject 1103 Clinical Sciences
Formatted abstract
The present study reports a two-year follow-up of psychological effects of predictive testing for Huntington's disease. Questionnaires assessing depression, general health, well-being, self injurious behavior, life satisfaction, and lifestyle were completed by 35 carriers and 58 non-carriers before the predictive test, and 2, 6, 12, and 24 months afterwards. Both carriers and non-carriers showed high suicidal ideation before the predictive testing. Depression scores and frequency of suicidal thoughts increased for carriers, compared to non-carriers, over time. There were no differences regarding life satisfaction or life style between carriers and non-carriers. Predictive testing was beneficial in reducing overall ill-health symptoms and increasing well-being for those initially expressing concern about Huntington's disease. The importance of assessing suicidal ideation and of continuing to provide adequate support is emphasized.
Keyword Huntington's disease
Presymptomatic
Psychosocial
Longitudinal
Predictive testing
Q-Index Code C1
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Mon, 18 Jan 2010, 12:19:05 EST by June Temby on behalf of Faculty Of Health Sciences