Stem cells and genetic disease

Mackay-Sim, A. and Silburn, P. (2008). Stem cells and genetic disease. In: Cell Proliferation. International Congress on Stem Cells: What Future for Therapy?, Rome, Italy, (85-93). 14-16 September 2006. doi:10.1111/j.1365-2184.2008.00487.x

Author Mackay-Sim, A.
Silburn, P.
Title of paper Stem cells and genetic disease
Conference name International Congress on Stem Cells: What Future for Therapy?
Conference location Rome, Italy
Conference dates 14-16 September 2006
Convener World Federation Cathol Med Assoc; Pontif Academy Life
Proceedings title Cell Proliferation   Check publisher's open access policy
Journal name Cell Proliferation   Check publisher's open access policy
Place of Publication Oxford, U.K.
Publisher Wiley-Blackwell Publishing
Publication Year 2008
Year available 2007
Sub-type Fully published paper
DOI 10.1111/j.1365-2184.2008.00487.x
ISSN 0960-7722
Volume 41
Issue Supp. 1
Start page 85
End page 93
Total pages 9
Language eng
Abstract/Summary Stem cell research is now a very broad field encompassing cells derived from all stages of life from the embryonic stem cells of the early blastocyst through to the adult stem cells of many tissues of the body. Adult stem cells from a variety of tissues are proving to be pluripotent and can differentiate into cell types different from the tissues from which they derive. Pre-clinical animal models indicate that adult stem cells do not cause tumours, not even, teratomas when transplanted. These properties, combined with the possibility of autologous transplantation, indicate significant advantages over embryonic stem cells in many proposed clinical applications. © 2008 The Authors, Journal compilation © 2008 Blackwell Publishing Ltd.
Subjects 0601 Biochemistry and Cell Biology
Keyword Adult stem cell
Brain development
Cell nucleus transplantation
Cell proliferation
Cystic fibrosis
Down syndrome
Embryonic stem cell
Genetic disorder
Genetic engineering
Hematopoietic stem cell
Mitochondrial gene
Parkinson disease
Pluripotent stem cell
Stem cell transplantation
Trisomy 21
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Journal special issue: The Proceedings of the lnternational Congress Stem Cells: What future for therapy? Scientific aspects and bioethical problems. Published Online: 20 Dec 2007

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Created: Fri, 15 Jan 2010, 16:23:20 EST by Jon Swabey on behalf of Faculty Of Health Sciences