Evolucao da funcao renal na fase aguda do infarto do miocardio como fator prognostico de eventos na fase intra-hospitalar e em um ano de seguimento

Pimenta, E., Ramos, R. F., Santos, E. S., Timerman, A. and Piegas, L. S. (2006) Evolucao da funcao renal na fase aguda do infarto do miocardio como fator prognostico de eventos na fase intra-hospitalar e em um ano de seguimento. Arquivos Brasileiros de Cardiologia, 86 3: 170-174. doi:10.1590/S0066-782X2006000300003


Author Pimenta, E.
Ramos, R. F.
Santos, E. S.
Timerman, A.
Piegas, L. S.
Title Evolucao da funcao renal na fase aguda do infarto do miocardio como fator prognostico de eventos na fase intra-hospitalar e em um ano de seguimento
Formatted title
Evolução da função renal na fase aguda do infarto do miocárdio como fator prognóstico de eventos na fase intra-hospitalar e em um ano de seguimento
Journal name Arquivos Brasileiros de Cardiologia   Check publisher's open access policy
ISSN 0066-782X
Publication date 2006-03-01
Year available 2006
Sub-type Article (original research)
DOI 10.1590/S0066-782X2006000300003
Open Access Status DOI
Volume 86
Issue 3
Start page 170
End page 174
Total pages 5
Place of publication Brazil
Publisher Arquivos Brasileiros de Cardiologia
Language eng
por
Subject 1102 Cardiovascular Medicine and Haematology
110201 Cardiology (incl. Cardiovascular Diseases)
1103 Clinical Sciences
110312 Nephrology and Urology
Abstract OBJECTIVE: To analyze the role of renal dysfunction at admission or during hospitalization in patients with acute myocardial infarction (AMI). METHODS: Two hundred and seventy-four patients with AMI were assessed between January 2000 and December 2001. Renal function was monitored by serum creatinine (Cr) measurement at admission and peak level during hospitalization. Creatinine clearance (CrCl) was estimated by the Cockcroft-Gault formula. In-hospital and one-year morbidity and mortality were evaluated. RESULTS: Mean age of the population studied was 62.2 ± 13.5, and 73% of the patients were male. Renal function was more reduced in male patients and in those with systemic arterial hypertension and prior CABG. Multivariate analysis showed higher hospital mortality rates associated with increased peak serum Cr levels (OR: 1.18 95% CI:1.18-2.77 p = 0.006), decreased baseline CrCl (OR:0.96 95% CI:0.93-0.99 p = 0.025) and peak CrCl (OR:0.96 95% CI:0.92-0.99 p = 0.023). Percent difference between baseline CrCl and the lowest CrCl obtained during hospitalization also indicated higher mortality rates (OR: 1.04 95% CI: 1.00-1.07 p = 0.033). No change was observed in the one-year morbidity and mortality from worsening of renal function. CONCLUSION: Renal dysfunction at admission and its deterioration during hospitalization have proved to be a major prognostic marker for immediate poor outcome.
Keyword Acute myocardial infarction
Renal insufficiency
Cardiovascular diseases
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes Translated title: Renal function outcome in acute myocardial infarction as a prognostic factor of in-hospital events and at one-year follow-up

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Fri, 15 Jan 2010, 20:00:30 EST by Macushla Boyle on behalf of Faculty Of Health Sciences