Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: Risk factors for acquisition, infection and their consequences

Playford, E. G., Craig, J. C. and Iredell, J. R. (2007) Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: Risk factors for acquisition, infection and their consequences. Journal of Hospital Infection, 65 3: 204-211. doi:10.1016/j.jhin.2006.11.010


Author Playford, E. G.
Craig, J. C.
Iredell, J. R.
Title Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: Risk factors for acquisition, infection and their consequences
Journal name Journal of Hospital Infection   Check publisher's open access policy
ISSN 0195-6701
1532-2939
Publication date 2007-03
Sub-type Article (original research)
DOI 10.1016/j.jhin.2006.11.010
Volume 65
Issue 3
Start page 204
End page 211
Total pages 8
Place of publication London, United Kingdom
Publisher W.B. Saunders
Language eng
Subject 11 Medical and Health Sciences
1103 Clinical Sciences
Abstract A retrospective case–control study was performed to assess risk factors and the clinical and economic consequences associated with acquisition of carbapenem-resistant Acinetobacter baumannii (CR-AB) in an intensive care unit (ICU) over a 24-month period. CR-AB was acquired by 64 of 1431 ICU admissions; each was matched with two controls. Risk factors associated with CR-AB acquisition included ICU-wide variables, such as ‘colonization pressure’ (the prevalence of ICU colonized patients) and ICU antibiotic use over the preceding three months, as well as patient-related variables. Among colonized patients, risk factors for CR-AB infection included transfusion and ‘colonization density’ (the proportion of body sites colonized with CR-AB). CR-AB infection was independently associated with increased hospital mortality [mortality difference: 20%; 95% confidence interval (CI): 1–40%], prolonged ICU stay (median length of stay difference: 15 days; 95% CI: 9–21 days) and prolonged hospital stay (30 days, 11–38 days) compared with matched controls.
Keyword Acinetobacter
Acinetobacter infections
Length of stay
Mortality
Case–control study
Cross infection
Intensive care unit
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 125 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 146 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 08 Jan 2010, 09:25:22 EST by Ms May Balasaize on behalf of School of Medicine