Active surveillance for Candidemia, Australia

Chen, Sharon, Slavin, Monica, Nguyen, Quoc, Marriot, Deborah, Playford, E. Geoffrey, Ellis, David, Sorrell, Tania and Australian Candidemia Study (2006) Active surveillance for Candidemia, Australia. Emerging Infectious Diseases, 12 10: 1508-1516.

Author Chen, Sharon
Slavin, Monica
Nguyen, Quoc
Marriot, Deborah
Playford, E. Geoffrey
Ellis, David
Sorrell, Tania
Australian Candidemia Study
Title Active surveillance for Candidemia, Australia
Formatted title Active surveillance for Candidemia, Australia
Journal name Emerging Infectious Diseases  (ERA 2012 Listed)    (ERA 2010 Rank A)   Check publisher's open access policy
Publication date 2006-10
Sub-type Article
Volume number 12
Issue number 10
ISSN 1080-6040
Start page 1508
End page 1516
Total pages 9
Place of publication Atlanta, GA, United States
Publisher National Center for Infectious Diseases
Language eng
Subject 11 Medical and Health Sciences
1103 Clinical Sciences
Abstract Population-based surveillance for candidemia in Australia from 2001 to 2004 identified 1,095 cases. Annual overall and hospital-specific incidences were 1.81/100,000 and 0.21/1,000 separations (completed admissions), respectively. Predisposing factors included malignancy (32.1%), indwelling vascular catheters (72.6%), use of antimicrobial agents (77%), and surgery (37.1%). Of 919 episodes, 81.5% were inpatient healthcare associated (IHCA), 11.6% were outpatient healthcare associated (OHCA), and 6.9% were community acquired (CA). Concomitant illnesses and risk factors were similar in IHCA and OHCA candidemia. IHCA candidemia was associated with sepsis at diagnosis (p<0.001), death <30 days after infection (p<0.001), and prolonged hospital admission (p<0.001). Non–Candida albicans species (52.7%) caused 60.5% of cases acquired outside hospitals and 49.9% of IHCA candidemia (p = 0.02). The 30-day death rate was 27.7% in those >65 years of age. Adult critical care stay, sepsis syndrome, and corticosteroid therapy were associated with the greatest risk for death. Systematic epidemiologic studies that use standardized definitions for IHCA, OHCA, and CA candidemia are indicated.
Keyword Australia
Candidemia
Health care
Population
Sepsis
Hospital Admissions
Clinical studies
Public Health
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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