The BiVACOR rotary biventricular assist device: Concept and in vitro investigation

Timms, Daniel, Fraser, John, Hayne, Mark, Dunning, John, McNeil, Keith and Pearcy, Mark (2008) The BiVACOR rotary biventricular assist device: Concept and in vitro investigation. Artificial Organs, 32 10: 816-819. doi:10.1111/j.1525-1594.2008.00633.x

Author Timms, Daniel
Fraser, John
Hayne, Mark
Dunning, John
McNeil, Keith
Pearcy, Mark
Title The BiVACOR rotary biventricular assist device: Concept and in vitro investigation
Journal name Artificial Organs   Check publisher's open access policy
ISSN 0160-564X
Publication date 2008-10
Sub-type Article (original research)
DOI 10.1111/j.1525-1594.2008.00633.x
Volume 32
Issue 10
Start page 816
End page 819
Total pages 4
Place of publication Cambridge, U.K.
Publisher Blackwel Science
Language eng
Subject 11 Medical and Health Sciences
1117 Public Health and Health Services
Abstract The BiVACOR is a novel rotary Biventricular Assist Device (BiVAD) undergoing development to treat global end-stage heart failure. The design includes left and right vanes positioned on a shared rotating hub to form a double-sided magnetically and hydrodynamically suspended centrifugal impeller. The performance of the device was assessed in a pulsatile mock circulation loop replicating end-stage biventricular heart failure, and was shown to restore flow from pathological (2 L/min) to normal levels (5 L/min). A novel technique to balance the left/right outflow of the BiVAD was also investigated, for which a maximum relative left to right outflow differential of 1.8 L/min was achieved at normal physiologic afterloads. The in vitro results encourage device progression to in vivo animal studies. Successful development of this BiVAD will provide a suitably miniature device for patients who require biventricular assistance.
Keyword Rotary blood pumps
Biventricular assist device
Heart failure
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 23 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 05 Jan 2010, 12:26:07 EST by Ms May Balasaize on behalf of Faculty Of Health Sciences