Nebulized hypertonic saline solution for acute bronchiolitis in infants: [Intervention Review]

Zhang, Linjie, Mendoza-Sassi, Raul A., Wainwright, Claire and Klassen, Terry P. (2009) Nebulized hypertonic saline solution for acute bronchiolitis in infants: [Intervention Review]. Cochrane Database of Systematic Reviews, 4: 1-23. doi:10.1002/14651858.CD006458.pub2


Author Zhang, Linjie
Mendoza-Sassi, Raul A.
Wainwright, Claire
Klassen, Terry P.
Title Nebulized hypertonic saline solution for acute bronchiolitis in infants: [Intervention Review]
Journal name Cochrane Database of Systematic Reviews   Check publisher's open access policy
ISSN 1469-493X
Publication date 2009
Sub-type Article (original research)
DOI 10.1002/14651858.CD006458.pub2
Open Access Status
Issue 4
Start page 1
End page 23
Total pages 23
Publisher John Wiley & Sons, Ltd
Language eng
Subject 11 Medical and Health Sciences
1114 Paediatrics and Reproductive Medicine
Abstract Acute viral bronchiolitis is the most common lower respiratory tract infection in infants, but the standard treatment remains supportive care. This review was conducted to assess the effects of nebulized hypertonic saline, which can increase clearance of mucus, in these patients. Four randomized trials involving 254 infants were included. Analysis of the pooled data suggests that nebulized 3% saline may significantly reduce the length of hospital stay and improve the clinical severity score in infants with acute viral bronchiolitis.There were no adverse effects noted with nebulized hypertonic saline when administered along with bronchodilators.
Keyword Bronchiolitis
Infants
Nebulized hypertonic saline
Q-Index Code C1
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Mon, 04 Jan 2010, 12:12:00 EST by Ms May Balasaize on behalf of Faculty Of Health Sciences