Metabolic syndrome and serum carotenoids: Findings of a cross-sectional study in Queensland, Australia

Coyne, Terry, Ibiebele, Torukiri I., Baade, Peter D., McClintock, Christine S. and Shaw, Jonathan E. (2009) Metabolic syndrome and serum carotenoids: Findings of a cross-sectional study in Queensland, Australia. British Journal of Nutrition, 102 11: 1668-1677. doi:10.1017/S000711450999081X

Author Coyne, Terry
Ibiebele, Torukiri I.
Baade, Peter D.
McClintock, Christine S.
Shaw, Jonathan E.
Title Metabolic syndrome and serum carotenoids: Findings of a cross-sectional study in Queensland, Australia
Journal name British Journal of Nutrition   Check publisher's open access policy
ISSN 0007-1145
Publication date 2009-12
Sub-type Article (original research)
DOI 10.1017/S000711450999081X
Volume 102
Issue 11
Start page 1668
End page 1677
Total pages 10
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Language eng
Formatted abstract
Several components of the metabolic syndrome, particularly diabetes and CVD, are known to be oxidative stress-related conditions and there is research to suggest that antioxidant nutrients may play a protective role in these conditions. Carotenoids are compounds derived primarily from plants and several have been shown to be potent antioxidant nutrients. The aim of the present study was to examine the associations between metabolic syndrome status and major serum carotenoids in adult Australians. Data on the presence of the metabolic syndrome, based on International Diabetes Federation 2005 criteria, were collected from 1523 adults aged 25 years and over in six randomly selected urban centres in Queensland, Australia, using a cross-sectional study design. Weight, height, BMI, waist circumference, blood pressure, fasting and 2 h blood glucose and lipids were determined, as well as five serum carotenoids. Mean serum a-, b-carotenes and the sum of the five carotenoid concentrations were significantly lower (P,0·05) in persons with the metabolic syndrome (after adjusting for age, sex, education, BMI status, alcohol intake, smoking, physical activity status and vitamin/mineral use) than persons without the syndrome. α-, β- and total carotenoids also decreased significantly (P,0·05) with increased number of components of the metabolic syndrome, after adjusting for these confounders. These differences were significant among former smokers and non-smokers, but not in present smokers. Low concentrations of serum α-, β-carotenes and the sum of five carotenoids appear to be associated with metabolic syndrome status. Additional research, particularly longitudinal studies, may help to determine whether these associations are causally related to the metabolic syndrome, or are a result of the pathologies of the syndrome.
Keyword Carotenoids
Metabolic syndrome
Cross-sectional studies
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Public Health Publications
Centre for Military and Veterans' Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 20 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 03 Jan 2010, 00:04:42 EST