Infants with chronic neonatal lung disease: recommendations for the use of home oxygen therapy

Fitzgerald, Dominic, Massie, R. John H., Nixon, Gillian M., Jaffe, Adam, Wilson, Andrew, Landau, Louis I., Twiss, Jacob, Smith, Greg, Wainwright, Claire and Harris, Margaret (2008) Infants with chronic neonatal lung disease: recommendations for the use of home oxygen therapy. Medical Journal of Australia, 189 10: 578-582.

Author Fitzgerald, Dominic
Massie, R. John H.
Nixon, Gillian M.
Jaffe, Adam
Wilson, Andrew
Landau, Louis I.
Twiss, Jacob
Smith, Greg
Wainwright, Claire
Harris, Margaret
Title Infants with chronic neonatal lung disease: recommendations for the use of home oxygen therapy
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 2008
Sub-type Article (original research)
Volume 189
Issue 10
Start page 578
End page 582
Total pages 5
Place of publication Strawberry Hills NSW, Australia
Publisher Australasian Medical Publication
Language eng
Subject 11 Medical and Health Sciences
1103 Clinical Sciences
Formatted abstract
Chronic neonatal lung disease (CNLD) is defined as a supplemental oxygen requirement beyond 36 weeks’ postmenstrual age, with more severely affected infants requiring oxygen beyond a full-term-equivalent age.

Low-flow supplemental oxygen facilitates discharge from hospital of infants with CNLD who develop hypoxia in air.

There is a lack of data on the most appropriate minimum mean target oxygen saturation (Spo2) level. Reflecting a variety of clinical practices and infant comorbidities (frequency of oxygen desaturation, presence of pulmonary hypertension, retinopathy of prematurity, and adequacy of growth), the minimum mean target range for Spo2 during overnight oximetry should be 93%–95%.

The effect of supplemental oxygen on carbon dioxide retention should be considered before deciding on an oxygen flow.

Most infants with CNLD are not ready for discharge until their supplemental oxygen requirement is ≤ 0.5 litres per minute delivered through a nasal cannula.

The safety of short-term disconnection from supplemental oxygen should be assessed before discharge.

Assessment of oxygenation during sleep with continuous overnight oximetry or polysomnography is recommended when weaning infants from supplemental oxygen.

Discontinuation of oxygen therapy is based on clinical assessments and documentation of adequate oxygenation in room air.

There is limited objective evidence on which to base recommendations.
Keyword Chronic neonatal lung disease (CNLD
Pulmonary Hypertension
Carbon Dioxide
Nasal Cannula
Clinical Studies
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Created: Thu, 24 Dec 2009, 10:56:49 EST by Ms May Balasaize on behalf of Faculty Of Health Sciences