Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds

Yi, Jing, Wei, Guangfeng, Huang, Xiaohui, Zhao, Lingzhi, Zhang, Quan and Yu, Chengzhong (2008) Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds. Journal of Sol-Gel Science and Technology, 45 1: 115-119. doi:10.1007/s10971-007-1668-x


Author Yi, Jing
Wei, Guangfeng
Huang, Xiaohui
Zhao, Lingzhi
Zhang, Quan
Yu, Chengzhong
Title Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds
Journal name Journal of Sol-Gel Science and Technology   Check publisher's open access policy
ISSN 0928-0707
1573-4846
Publication date 2008-01-01
Sub-type Article (original research)
DOI 10.1007/s10971-007-1668-x
Volume 45
Issue 1
Start page 115
End page 119
Total pages 5
Place of publication Boston, MA, U.S.A
Publisher Kluwer Academic Publishers
Language eng
Subject 1007 Nanotechnology
06 Biological Sciences
Abstract Mesoporous bioactive glass (MBG) fibers have been synthesized using the combination of a sol–gel process and a high velocity spray procedure by carefully controlling the sol composition, acidity and water content. A three-dimensional (3D) macro-structure with ∼50–100 μm interconnected macropores is formed in the spraying process. The MBG fibers possess well-ordered hexagonal mesostructure and excellent in vitro bioactivities. Sprague–Dawley (SD) rat osteoblasts have been cultured on MBG fibers. It is found that the MBG fibers have good cell biocompatibility and the 3D macro-structure is beneficial for cell attachment. It is anticipated that MBG fibers with controlled mesostructure and excellent in vitro bioactivity are good candidates for future tissue-engineering scaffolds.
Keyword Mesoporous
Bioactive glass
Sol–gel
Fibers
Tissue-engineering
Q-Index Code C1
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
Centre for Nanotechnology and Biomaterials Publications
 
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Created: Tue, 22 Dec 2009, 01:31:56 EST by Ms Lynette Adams on behalf of Centre for Nanotechnology and Biomaterials