Baseline and follow-up assessment of regional left ventricular volume using 3-dimensional echocardiography: Comparison with cardiac magnetic resonance

Jenkins, Carly and Marwick, Thomas H. (2009) Baseline and follow-up assessment of regional left ventricular volume using 3-dimensional echocardiography: Comparison with cardiac magnetic resonance. Cardiovascular Ultrasound, 7 1: . doi:10.1186/1476-7120-7-55


Author Jenkins, Carly
Marwick, Thomas H.
Title Baseline and follow-up assessment of regional left ventricular volume using 3-dimensional echocardiography: Comparison with cardiac magnetic resonance
Journal name Cardiovascular Ultrasound   Check publisher's open access policy
ISSN 1476-7120
Publication date 2009-11
Sub-type Article (original research)
DOI 10.1186/1476-7120-7-55
Open Access Status DOI
Volume 7
Issue 1
Total pages 8
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Formatted abstract
The assessment of regional volumes is an option for analysis of the response of LV segments to interventions such as revascularization or cell therapy. We sought to compare regional volumes from 3D-echocardiography (3DE) with cardiac magnetic resonance (CMR) over follow-up.

CMR regional volumes were assessed at baseline and after one year follow-up in 30 unselected patients (28 men, 65 ± 11 years) presenting for evaluation of cardiac function with previous infarction. 3DE images were also gathered over 4 cardiac cycles and measurements were performed off-line. CMR images were obtained using a 1.5 Tesla scanner and measured offline by method of landmarks and by centre of mass. Regional volumes were measured at end-diastole (rEDV) and end-systole (rESV) and the change in volume was compared for each over follow-up.

There was good correlation between 3DE and both CMR methods at baseline and follow-up. Changes in rEDV with 3DE vs CMRL were comparable (0.11 ± 3 ml vs 0.12 ± 3 ml, p = 0.94), as was change in CMRM (0.26 ± 2 ml, p = 0.69). However the change in regional volume by 3DE and CMRL correlated poorly (r = 0.03, p = 0.68), as did change in 3DE vs CMRM (r = 0.04, p = 0.65). Similarly, changes in rESV with 3DE and CMRL were similar (0.27 ± 2 ml vs 0.36 ± 2 ml, p = 0.70), as was change in CMRM (0.05 ± 1 ml, p = 0.31). Again, correlations between rESV by 3DE vs CMRL were poor (r = 0.03, p = 0.72), as well as 3DE vs CMRM (r = 0.07, p = 0.40).

Although global 3DE volumes compare well with CMR volumes, new developments in image quality and automated software will be needed before changes in regional volumes can be reliably followed with 3DE.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Article # 55

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Sun, 20 Dec 2009, 00:04:46 EST