Environmental shotgun sequencing

Tyson, Gene W. and Hugenholtz, Philip (2005). Environmental shotgun sequencing. In Lynn B. Jorde (Ed.), Encyclopedia of genetics, genomics, proteomics, and bioinformatics (pp. 1386-1391) West Sussex, U.K.: John Wiley & Sons. doi:10.1002/047001153X.g205313


Author Tyson, Gene W.
Hugenholtz, Philip
Title of chapter Environmental shotgun sequencing
Title of book Encyclopedia of genetics, genomics, proteomics, and bioinformatics
Place of Publication West Sussex, U.K.
Publisher John Wiley & Sons
Publication Year 2005
Sub-type Chapter in textbook
DOI 10.1002/047001153X.g205313
Series Encyclopedia of genetics, genomics, proteomics, and bioinformatics
ISBN 9780470849743
0470849746
Editor Lynn B. Jorde
Volume number 3-4: Genomics
Chapter number 68
Start page 1386
End page 1391
Total pages 6
Total chapters 108
Language eng
Subjects 060408 Genomics
0605 Microbiology
Formatted Abstract/Summary
Shotgun sequencing of microbial communities is a promising means for delving into community function and interactions, population structure and dynamics, and bypassing the cultivation bottleneck in microbiology. However, this approach is mostly blind to low-abundance species as it effectively samples only the dominant populations in a community. It also faces a number of technical challenges such as the assembly and separation of individual genomes from a mixture of genomic fragments compounded by sampling unevenness and data scalability. Despite these limitations, environmental shotgun sequencing should rapidly advance the fields of microbial ecology and evolution.
Keyword Environmental shotgun sequencing
Microbial ecology
Genomics
Microbial ecology and evolution
Communities
Shotgun sequencing
Genome assembly
Q-Index Code BX
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Published as Chapter 65 of 103 chapters, with 5 additional unnumbered chapters in the Volume. eBook (DOIs, below) is the 3rd Edition: ISBN 9780470011539; 047001153X.

 
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Created: Fri, 18 Dec 2009, 10:26:15 EST by Michael Affleck on behalf of Faculty of Science