Differences in plasma caffeine appearance rates between and within subjects following caffeine ingestion

Skinner, T., Gaulke, S., Leveritt, M., Coombes, J., Taaffe, D. and Jenkins, D. (2009). Differences in plasma caffeine appearance rates between and within subjects following caffeine ingestion. In: Journal of Science and Medicine in Sport: Program and Abstracts - be active '09. 2009 Australian Conference of Science and Medicine in Sport - be active '09, Brisbane, Qld, Australia, (e28-e28). 14-17 October, 2009. doi:10.1016/j.jsams.2009.10.057


Author Skinner, T.
Gaulke, S.
Leveritt, M.
Coombes, J.
Taaffe, D.
Jenkins, D.
Title of paper Differences in plasma caffeine appearance rates between and within subjects following caffeine ingestion
Formatted title

Conference name 2009 Australian Conference of Science and Medicine in Sport - be active '09
Conference location Brisbane, Qld, Australia
Conference dates 14-17 October, 2009
Proceedings title Journal of Science and Medicine in Sport: Program and Abstracts - be active '09   Check publisher's open access policy
Place of Publication Amsterdam, The Netherlands
Publisher Elsevier
Publication Year 2009
DOI 10.1016/j.jsams.2009.10.057
ISSN 1440-2440
Volume 12
Issue Suppl. 2
Start page e28
End page e28
Total pages 1
Language eng
Formatted Abstract/Summary
Purpose:
Previous research in our laboratory has suggested that individuals absorb and metabolise caffeine at different rates and this may partially explain the disparity in results between studies that have examined the ergogenic potential of caffeine with athletes engaged in brief high intensity exercise. The aim of the present study was to determine differences in plasma caffeine appearance rates between and within individuals.

Methods:
On two occasions separated by seven days, six healthy active male volunteers were administered a capsule of 6 mg kg−1 caffeine following a 12 h fast. Blood was sampled via venipuncture at baseline and again 30, 60 and 90 min post-ingestion for later analysis of caffeine.

Results:

Differences in caffeine absorption and appearance rates were found between subjects with a coefficient of variation for inter-subject sampling of 29.25%. Significant variation in venous blood caffeine concentrations was found within subjects (r = 0.59; p < 0.001).

Conclusion:
There is considerable within-subject variation in caffeine appearance in the blood following caffeine ingestion. While the reasons for the variation are not clear, there are implications with regard to the timing of caffeine intake and its ergogenic potential, particularly for athletes engaged in relatively brief high intensity activities.

Subjects EX
110602 Exercise Physiology
950102 Organised Sports
111101 Clinical and Sports Nutrition
Q-Index Code EX
Q-Index Status Provisional Code

Document type: Conference Paper
Collection: School of Human Movement and Nutrition Sciences Publications
 
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Created: Mon, 07 Dec 2009, 21:13:28 EST by Deborah Noon on behalf of School of Human Movement and Nutrition Sciences