Treatment recommendations for psoriatic arthritis

Ritchlin, C. T., Kavanaugh, A., Gladman, D. D., Mease, P. J., Helliwell, P., Boehncke, W. H., de Vlam, K., Fiorentino, D., FitzGerald, O., Gottlieb, A. B., McHugh, N. J., Nash, P., Qureshi, A. A., Soriano, E. R. and Taylor, W. J. (2009) Treatment recommendations for psoriatic arthritis. Annals of the Rheumatic Diseases, 68 9: 1387-1394. doi:10.1136/ard.2008.094946

Author Ritchlin, C. T.
Kavanaugh, A.
Gladman, D. D.
Mease, P. J.
Helliwell, P.
Boehncke, W. H.
de Vlam, K.
Fiorentino, D.
FitzGerald, O.
Gottlieb, A. B.
McHugh, N. J.
Nash, P.
Qureshi, A. A.
Soriano, E. R.
Taylor, W. J.
Title Treatment recommendations for psoriatic arthritis
Journal name Annals of the Rheumatic Diseases   Check publisher's open access policy
ISSN 0003-4967
Publication date 2009-09
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1136/ard.2008.094946
Volume 68
Issue 9
Start page 1387
End page 1394
Total pages 8
Place of publication London, United Kingdom
Publisher British Medical Journal Publishing Group
Language eng
Subject 1103 Clinical Sciences
Abstract Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion. Methods: Formal literature reviews of treatment for the most significant discrete clinical manifestations of PsA (skin and nails, peripheral arthritis, axial disease, dactylitis and enthesitis) were performed and published by members of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). Treatment recommendations were drafted for each of the clinical manifestations by rheumatologists, dermatologists and PsA patients based on the literature reviews and consensus opinion. The level of agreement for the individual treatment recommendations among GRAPPA members was assessed with an online questionnaire. Results: Treatment recommendations were developed for peripheral arthritis, axial disease, psoriasis, nail disease, dactylitis and enthesitis in the setting of PsA. In rotal, 19 recommendations were drafted, and over 80% agreement was obtained on 16 of them. In addition, a grid that factors disease severity into each of the different disease manifestations was developed to help the clinician with treatment decisions for the individual patient from an evidenced-based perspective. Conclusions: Treatment recommendations for the cardinal physical manifestations of PsA were developed based on a literature review and consensus between rheumatologists and dermatologists. In addition, a grid was established to assist in therapeutic reasoning and decision making for individual patients. It is anticipated that periodic updates will take place using this framework as new data become available.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
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Created: Mon, 23 Nov 2009, 15:25:32 EST