Natural infection of the ground squirrel (Spermophilus spp.) with Echinococcus granulosus in China

Yang, Yu Rong, Liu, Tianxi, Bai, Xueli, Boufana, Belgees, Craig, Philip S., Nakao, Minoru, Ito, Akira, Zhang, Jan Zhong, Giraudoux, Patrick and McManus, Donald P. (2009) Natural infection of the ground squirrel (Spermophilus spp.) with Echinococcus granulosus in China. PLoS Neglected Tropical Diseases, 3 9: Article number e518. doi:10.1371/journal.pntd.0000518

Author Yang, Yu Rong
Liu, Tianxi
Bai, Xueli
Boufana, Belgees
Craig, Philip S.
Nakao, Minoru
Ito, Akira
Zhang, Jan Zhong
Giraudoux, Patrick
McManus, Donald P.
Title Natural infection of the ground squirrel (Spermophilus spp.) with Echinococcus granulosus in China
Formatted title
Natural Infection of the Ground Squirrel (Spermophilus spp.) with Echinococcus granulosus in China
Journal name PLoS Neglected Tropical Diseases   Check publisher's open access policy
ISSN 1935-2727
Publication date 2009-09
Year available 2009
Sub-type Article (original research)
DOI 10.1371/journal.pntd.0000518
Open Access Status DOI
Volume 3
Issue 9
Start page Article number e518
Total pages 4
Editor Peter Hotez
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Collection year 2010
Language eng
Subject 9204 Public Health (excl. Specific Population Health)
1117 Public Health and Health Services
Formatted abstract
Echinococcus granulosus is usually transmitted between canid definitive hosts and ungulate intermediate hosts.

Methodology/Principal Findings:
Lesions found in the livers of ground squirrels, Spermophilus dauricus/alashanicus, trapped in Ningxia Hui Autonomous Region, an area in China co-endemic for both E. granulosus and E. multilocularis, were subjected to molecular genotyping for Echinococcus spp. DNA. One of the lesions was shown to be caused by E. granulosus and subsequently by histology to contain viable protoscoleces.

This is the first report of a natural infection of the ground squirrel with E. granulosus. This does not provide definitive proof of a cycle involving ground squirrels and dogs or foxes, but it is clear that there is active E. granulosus transmission occurring in this area, despite a recent past decline in the dog population in southern Ningxia.
Keyword Tibet plateau region
Fox vulpes-vulpes
Cystic echinococcosis
Alveolar echinococcosis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 7 times in Scopus Article | Citations
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Created: Thu, 12 Nov 2009, 11:56:57 EST by Mr Andrew Martlew on behalf of School of Public Health