A comparative study of the spatial distribution of schistosomiasis in Mali in 1984-1989 and 2004-2006

Clements, Archie C. A., Bosque-Oliva, Elisa, Sacko, Moussa, Landoure, Aly, Dembele, Robert, Traore, Mamadou, Coulibaly, Godefroy, Gabrielli, Albis F., Fenwick, Alan and Brooker, Simon (2009) A comparative study of the spatial distribution of schistosomiasis in Mali in 1984-1989 and 2004-2006. PLoS Neglected Tropical Diseases, 3 5: e431.1-e431.11. doi:10.1371/journal.pntd.0000431

Author Clements, Archie C. A.
Bosque-Oliva, Elisa
Sacko, Moussa
Landoure, Aly
Dembele, Robert
Traore, Mamadou
Coulibaly, Godefroy
Gabrielli, Albis F.
Fenwick, Alan
Brooker, Simon
Title A comparative study of the spatial distribution of schistosomiasis in Mali in 1984-1989 and 2004-2006
Journal name PLoS Neglected Tropical Diseases   Check publisher's open access policy
ISSN 1935-2727
Publication date 2009-05
Year available 2009
Sub-type Article (original research)
DOI 10.1371/journal.pntd.0000431
Open Access Status DOI
Volume 3
Issue 5
Start page e431.1
End page e431.11
Total pages 11
Place of publication Maryland Heights, MO, United States
Publisher PLoS Neglected Tropical Diseases
Collection year 2010
Language eng
Subject C1
9204 Public Health (excl. Specific Population Health)
1117 Public Health and Health Services
Formatted abstract
Background: We investigated changes in the spatial distribution of schistosomiasis in Mali following a decade of donorfunded control and a further 12 years without control.

Methodology/Principal Findings: National pre-intervention cross-sectional schistosomiasis surveys were conducted in Mali in 1984–1989 (in communities) and again in 2004–2006 (in schools). Bayesian geostatistical models were built separately for each time period and on the datasets combined across time periods. In the former, data from one period were used to predict prevalence of schistosome infections for the other period, and in the latter, the models were used to determine whether spatial autocorrelation and covariate effects were consistent across periods. Schistosoma haematobium prevalence was 25.7% in 1984–1989 and 38.3% in 2004–2006; S. mansoni prevalence was 7.4% in 1984–1989 and 6.7% in 2004–2006 (note the models showed no significant difference in mean prevalence of either infection between time periods). Prevalence of both infections showed a focal spatial pattern and negative associations with distance from perennial waterbodies, which was consistent across time periods. Spatial models developed using 1984–1989 data were able to predict the distributions of both schistosome species in 2004–2006 (area under the receiver operating characteristic curve was typically .0.7) and vice versa.

Conclusions/Significance: A decade after the apparently successful conclusion of a donor-funded schistosomiasis control programme from 1982–1992, national prevalence of schistosomiasis had rebounded to pre-intervention levels. Clusters of schistosome infections occurred in generally the same areas accross time periods, although the precise locations varied. To achieve long-term control, it is essential to plan for sustainability of ongoing interventions, including stengthening endemic country health systems. 
Keyword Urinary Schistosomiasis
Risk models
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
ERA 2012 Admin Only
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 59 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 61 times in Scopus Article | Citations
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Created: Fri, 04 Sep 2009, 10:27:45 EST