Bilateral tremor relations in Parkinson's disease: Effects of mechanical coupling and medication

Morrison, S., Kerr, G. and Silburn, P. (2008) Bilateral tremor relations in Parkinson's disease: Effects of mechanical coupling and medication. Parkinsonism and Related Disorders, 14 4: 298-308. doi:10.1016/j.parkreldis.2007.09.004


Author Morrison, S.
Kerr, G.
Silburn, P.
Title Bilateral tremor relations in Parkinson's disease: Effects of mechanical coupling and medication
Journal name Parkinsonism and Related Disorders   Check publisher's open access policy
ISSN 1353-8020
1873-5126
Publication date 2008-05
Year available 2007
Sub-type Article (original research)
DOI 10.1016/j.parkreldis.2007.09.004
Volume 14
Issue 4
Start page 298
End page 308
Total pages 11
Place of publication Oxford, United Kingdom
Publisher Elsevier
Language eng
Abstract The aim of the present study was to examine the dynamics of bilateral multiple segment resting and postural tremor in 12 young, older subjects and eight Parkinson’s (PD) patients in their different medication states. A second aim was to investigate whether bilateral independence of upper limb tremor was preserved for PD patients with amplified tremor under conditions where no upper limb segment was supported. Under these conditions, the likelihood for mechanical transmission between segments was increased. Tremor was recorded, bilaterally, from the hand and finger segments of all subjects. In addition to the PD subjects exhibiting greater tremor under both on/off medication states than the young/old control subjects, the tremor increase within limb from the hand to the finger was 2–3 times greater for the PD group in comparison to the healthy subjects. Despite this increased tremor, no differences were observed in the level of coupling between limbs across groups. Furthermore, the degree of coupling between limbs for the PD group was unaffected by their medication state. Overall, these results demonstrate that bilateral independence of tremor in PD participants is preserved despite conditions which maximised the chance of increased coupling.
Keyword Parkinson's disease
Resting tremor
Postural tremor
Bimanual coupling
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Available online 31 October 2007.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Thu, 03 Sep 2009, 09:48:41 EST by Mr Andrew Martlew on behalf of School of Medicine