John Eccles (1903-97) and the experiment that proved chemical synaptic transmission in the central nervous system

Todman, Don (2008) John Eccles (1903-97) and the experiment that proved chemical synaptic transmission in the central nervous system. Journal of Clinical Neuroscience, 15 9: 972-977. doi:10.1016/j.jocn.2008.01.001


Author Todman, Don
Title John Eccles (1903-97) and the experiment that proved chemical synaptic transmission in the central nervous system
Journal name Journal of Clinical Neuroscience   Check publisher's open access policy
ISSN 0967-5868
1532-2653
Publication date 2008-09
Sub-type Article (original research)
DOI 10.1016/j.jocn.2008.01.001
Volume 15
Issue 9
Start page 972
End page 977
Total pages 6
Place of publication Kidlington, Oxford, United Kingdom
Publisher Churchill Livingstone
Language eng
Abstract One of the most important experiments in neurophysiology in the twentieth century took place in the physiology laboratories at the University of Otago, New Zealand, in August 1951. The group of researchers led by John Eccles convincingly established that synaptic transmission in the central nervous system was a chemical process. This work was the culmination of a long debate between advocates of electrical and chemical transmission. The conclusions overturned Eccles’s previous theories of an electrical “Golgi-cell” mechanism and represent a pivotal moment in the history of neuroscience.
Keyword Neuroscience history
Chemical synaptic transmission
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Thu, 03 Sep 2009, 08:31:23 EST by Mr Andrew Martlew on behalf of School of Medicine