Counting of obscure events: A Bayesian approach

Gruber, Daniel and Plakhotnik, Taras (2009) Counting of obscure events: A Bayesian approach. Chemical Physics Letters, 474 4-6: 371-374. doi:10.1016/j.cplett.2009.04.060


Author Gruber, Daniel
Plakhotnik, Taras
Title Counting of obscure events: A Bayesian approach
Journal name Chemical Physics Letters   Check publisher's open access policy
ISSN 0009-2614
Publication date 2009-06-04
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.cplett.2009.04.060
Volume 474
Issue 4-6
Start page 371
End page 374
Total pages 4
Editor D. C. Clary
M. Okumura
V. Sundstrom
Place of publication Netherlands
Publisher Elsevier BV
Collection year 2010
Language eng
Subject C1
970102 Expanding Knowledge in the Physical Sciences
0299 Other Physical Sciences
Abstract A general method for counting of obscure events in presence of detection noise is presented. The method combines the measurement data with additional information about the system under investigation to improve the measurement accuracy with the help of probability theory. As an example, we apply the method to the case of counting molecules in a microfluidic device and show in simulations that the accuracy is always better than for a thresholding approach. As a second example, we show how it can be used for photon counting at high count rates with an electron multiplying CCD (EMCCD) camera.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
2010 Higher Education Research Data Collection
 
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Created: Thu, 03 Sep 2009, 08:05:05 EST by Mr Andrew Martlew on behalf of Physics