Improving Adsorbent Properties of Cage-like Ordered Amine Functionalized Mesoporous Silica with Very Large Pores for Bioadsorption

Hartono, S.B., Qiao, S.Z., Jack, K.S., Ladewig, B.P., Hao, Z.P. and Lu, G.Q. (2009) Improving Adsorbent Properties of Cage-like Ordered Amine Functionalized Mesoporous Silica with Very Large Pores for Bioadsorption. LANGMUIR, 25 11: 6413-6424. doi:10.1021/la900023p


Author Hartono, S.B.
Qiao, S.Z.
Jack, K.S.
Ladewig, B.P.
Hao, Z.P.
Lu, G.Q.
Title Improving Adsorbent Properties of Cage-like Ordered Amine Functionalized Mesoporous Silica with Very Large Pores for Bioadsorption
Journal name LANGMUIR   Check publisher's open access policy
ISSN 0743-7463
Publication date 2009-06-02
Year available 2009
Sub-type Article (original research)
DOI 10.1021/la900023p
Volume 25
Issue 11
Start page 6413
End page 6424
Total pages 12
Editor David G Whitten
Place of publication United States
Publisher American Chemical Society
Collection year 2010
Language eng
Subject C1
090403 Chemical Engineering Design
100703 Nanobiotechnology
920405 Environmental Health
Formatted abstract
In this paper, we report the successful synthesis of amine-functionalized FDU-12-type mesoporous silica with a very large pore (30.2 rim) and a highly ordered mesostructure by using 3-aminopropyltriethoxysilane (APTES) as an organosilane source. Small angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) measurements confirmed that the materials possessed a face-centered cubic (space group Fm (3) over barm) mesostructure. Different techniques were used to obtain a significant pore and entrance size enlargement: low synthesis temperature and high hydrothermal treatment temperature. The amount of amine organosilane influenced the mesostructure of the mesoporous silica. It was found that the addition of inorganic salt (KCl) could help to maintain an ordered structure of the large pore mesoporous material. X-ray photoelectron spectroscopy (XPS), solid-state magic-angle spinning (MAS) C-13 nuclear magnetic resonance (NMR) and thermogravimetric analysis (TGA) verified the incorporation of amine functional groups on the surface of the materials. The addition of amine organosilane extended the synthesis temperature domain of ordered FDU-12 materials. The amine functional group significantly enhanced the adsorption capacity of the mesoporous materials, e.g., the amine functionalized mesoporous silica had 8-fold higher bovine serum albumin (BSA) adsorption capacity than that of the unfunctionalized one. It also had 2 times higher adsorption capacity for large cellulase enzymes. The amine functional group introduced positively charged groups on the surface of the mesoporous silica, which created strong electrostatic interactions between the protein and the silica.
© 2009 American Chemical Society
Keyword INORGANIC-ORGANIC HYBRID
Molecular-sieve
SYNTHESIS TEMPERATURE
DRUG-DELIVERY
MCM-41
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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Created: Thu, 03 Sep 2009, 07:59:18 EST by Mr Andrew Martlew on behalf of Aust Institute for Bioengineering & Nanotechnology