Physical activity and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Johnsen, Nina Fons, Tjonneland, Anne, Thomsen, Birthe L. R., Christensen, Jane, Loft, Steffen, Friedenreich, Christine, Key, Timothy J., Allen, Naomi E., Lahmann, Petra H., Mejlvig, Lotte, Overvad, Kim, Kaaks, Rudolf, Rohrmann, Sabine, Boing, Heiner, Misirli, Gesthimani, Trichopoulou, Antonia, Zylis, Dimosthenis, Tumino, Rosario, Pala, Valeria, Bueno-de-Mesquita, H. Bas, Kiemeney, Lambertus A., Suarez, Laudina Rodriguez, Gonzalez, Carlos A., Sanchez, Maria Jose, Huerta, Jose Maria, Gurrea, Aurelio Barricate, Manjer, Jonas, Wirfalt, Elisabet, Khaw, Kay-Tee, Wareham, Nick, Boffetta, Paolo, Egevad, Lars, Rinaldi, Sabina and Riboli, Elio (2009) Physical activity and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. International Journal of Cancer, 125 4: 902-908. doi:10.1002/ijc.24326


Author Johnsen, Nina Fons
Tjonneland, Anne
Thomsen, Birthe L. R.
Christensen, Jane
Loft, Steffen
Friedenreich, Christine
Key, Timothy J.
Allen, Naomi E.
Lahmann, Petra H.
Mejlvig, Lotte
Overvad, Kim
Kaaks, Rudolf
Rohrmann, Sabine
Boing, Heiner
Misirli, Gesthimani
Trichopoulou, Antonia
Zylis, Dimosthenis
Tumino, Rosario
Pala, Valeria
Bueno-de-Mesquita, H. Bas
Kiemeney, Lambertus A.
Suarez, Laudina Rodriguez
Gonzalez, Carlos A.
Sanchez, Maria Jose
Huerta, Jose Maria
Gurrea, Aurelio Barricate
Manjer, Jonas
Wirfalt, Elisabet
Khaw, Kay-Tee
Wareham, Nick
Boffetta, Paolo
Egevad, Lars
Rinaldi, Sabina
Riboli, Elio
Title Physical activity and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
Journal name International Journal of Cancer   Check publisher's open access policy
ISSN 0020-7136
1097-0215
Publication date 2009-08
Sub-type Article (original research)
DOI 10.1002/ijc.24326
Volume 125
Issue 4
Start page 902
End page 908
Total pages 7
Place of publication John Wiley and Sons
Publisher Hoboken, NJ, United States
Language eng
Formatted abstract
The evidence concerning the possible association between physical activity and the risk of prostate cancer is inconsistent and additional data are needed. We examined the association between risk of prostate cancer and physical activity at work and in leisure time in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. In our study, including 127,923 men aged 20–97 years from 8 European countries, 2,458 cases of prostate cancer were identified during 8.5 years of followup. Using the Cox proportional hazards model, we investigated the associations between prostate cancer incidence rate and occupational activity and leisure time activity in terms of participation in sports, cycling, walking and gardening; a metabolic equivalent (MET) score based on weekly time spent on the 4 activities; and a physical activity index. MET hours per week of leisure time activity, higher score in the physical activity index, participation in any of the 4 leisure time activities, and the number of leisure time activities in which the participants were active were not associated with prostate cancer incidence. However, higher level of occupational physical activity was associated with lower risk of advanced stage prostate cancer (ptrend 5 0.024). In conclusion, our data support the hypothesis of an inverse association between advanced prostate cancer risk and occupational physical activity, but we found no support for an association between prostate cancer risk and leisure time physical activity.
Keyword Physical activity
Exercise
Prostate cancer
Cohort
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
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Created: Thu, 03 Sep 2009, 07:45:52 EST by Mr Andrew Martlew on behalf of School of Public Health