Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins

Marshall, R. D., Rand, J. S. and Morton, J. M. (2009) Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins. Journal of Feline Medicine and Surgery, 11 8: 683-691. doi:10.1016/j.jfms.2009.05.016


Author Marshall, R. D.
Rand, J. S.
Morton, J. M.
Title Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins
Journal name Journal of Feline Medicine and Surgery   Check publisher's open access policy
ISSN 1098-612X
Publication date 2009-08-01
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.jfms.2009.05.016
Volume 11
Issue 8
Start page 683
End page 691
Total pages 9
Editor A. H. Sparkes
M. Scherk
Place of publication London, UK
Publisher Elsevier
Collection year 2010
Language eng
Subject 0707 Veterinary Sciences
C1
Abstract Glycaemic control and remission probabilities were compared in 24 newly diagnosed diabetic cats treated twice daily with either glargine, protamine zinc (PZI) or lente insulin and fed a low carbohydrate diet. After day 17, the probability of remission was substantially higher for cats with lower mean 12 h blood glucose concentrations on day 17, irrespective of insulin type. Glargine-treated cats had lower mean 12 h blood glucose concentrations on day 17 than PZI- or lente-treated cats, and all eight glargine-treated cats achieved remission compared to three PZI- and two lente-treated cats. The probability of remission was greater for cats treated with glargine than cats treated with PZI or lente insulin. In newly diagnosed diabetic cats, twice daily treatment with glargine provides better glycaemic control and higher probability of remission compared to twice daily treatment with PZI or lente insulin. Good glycaemic control soon after diagnosis is associated with increased probability of remission and should be the goal of insulin therapy.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Veterinary Science Publications
 
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Created: Thu, 03 Sep 2009, 17:42:01 EST by Mr Andrew Martlew on behalf of School of Veterinary Science