Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome complicated by aneurysmal aortitis

Ng, Chin Soon, Hogan, Patrick, McKenzie, Scott, Gibbs, Harry, Strutton, Geoff and Wong, Richard (2007) Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome complicated by aneurysmal aortitis. Journal of Clinical Rheumatology, 13 4: 221-223. doi:10.1097/RHU.0b013e3181337820


Author Ng, Chin Soon
Hogan, Patrick
McKenzie, Scott
Gibbs, Harry
Strutton, Geoff
Wong, Richard
Title Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome complicated by aneurysmal aortitis
Journal name Journal of Clinical Rheumatology   Check publisher's open access policy
ISSN 1076-1608
Publication date 2007-01-01
Sub-type Article (original research)
DOI 10.1097/RHU.0b013e3181337820
Volume 13
Issue 4
Start page 221
End page 223
Total pages 3
Place of publication Philadelphia, PA, U.S.A.
Publisher Lippincott Williams & Wilkins
Collection year 2008
Language eng
Subject CX
920108 Immune System and Allergy
110322 Rheumatology and Arthritis
Abstract "MAGIC syndrome" (Mouth And Genital ulcers with Inflamed Cartilage) has been proposed to describe patients with clinical features of both relapsing polychondritis and Behcet disease. A total of 18 cases have been reported with only I case associated with aneursymal aortitis described in 1997. Herein, we describe a patient with MAGIC syndrome complicated by aneurysmal aortitis requiring cardiothoracic surgery and intensive immunosuppression. Monitoring for the possible development of inflammatory aortic aneurysms should thus be considered in patients with MAGIC syndrome who have persistently elevated serum inflammatory markers. If an aortic aneurysm is detected, cardiothoracic surgical referral is necessary, close monitoring for enlargement is mandatory, and intensification of immunosuppressive therapy should be considered.
Keyword MAGIC
Behcet disease
relapsing polychondritis
aneurysmal aortitis
Q-Index Code CX

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Wed, 26 Aug 2009, 19:50:36 EST by Denise Wilson on behalf of Medicine - Princess Alexandra Hospital