Maternal and fetal risk factors associated with severity of hypospadias: A comparison of mild and severe cases

Carlson, William H., Kisely, Stephen R. and MacLellan, Dawn L. (2009) Maternal and fetal risk factors associated with severity of hypospadias: A comparison of mild and severe cases. Journal of Pediatric Urology, 5 4: 283-286. doi:10.1016/j.jpurol.2008.12.005


Author Carlson, William H.
Kisely, Stephen R.
MacLellan, Dawn L.
Title Maternal and fetal risk factors associated with severity of hypospadias: A comparison of mild and severe cases
Journal name Journal of Pediatric Urology   Check publisher's open access policy
ISSN 1477-5131
1873-4898
Publication date 2009-08-01
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.jpurol.2008.12.005
Volume 5
Issue 4
Start page 283
End page 286
Total pages 4
Editor David Frank
Place of publication New York, United States
Publisher Elsevier BV
Collection year 2010
Language eng
Subject 11 Medical and Health Sciences
1114 Paediatrics and Reproductive Medicine
C1
Formatted abstract
Objective: To determine maternal and fetal demographic factors which predict the risk of increasing severity of hypospadias.

Patients and methods:A population-based study using the Nova Scotia Atlee Perinatal Database was performed. Demographic variables of mothers and boys with hypospadias were obtained from 1980 to 2007 inclusive. Hypospadias was graded by the position of the urinary meatus as glanular, coronal, shaft, or proximal to shaft. Maternal and fetal risk factors for hypospadias severity were compared using logistic regression.

Results:The total number of male pregnancy and birth records during the study period was 130,796. The total number of cases of hypospadias was 995, yielding an incidence of 0.76%. The severity of hypospadias was graded as glanular in 428 (77.8%); coronal in 77 (14%); penile shaft in 34 (6.2%); and proximal to the penile shaft in 12 (2.2%). The severity of hypospadias was not graded in 445 cases. Low birth weight, low gestational age and maternal age were associated with increased severity of hypospadias, but only maternal age (P < 0.03) when logistic regression was performed. Limitations included self-reporting for some parameters, such as smoking, and lack of data, such as for the use of assisted reproductive technologies.

Conclusions:Advanced maternal age was associated with increased severity of hypospadias in our population.
Keyword Hypospadias
Maternal
Fetal risk factors
Comparison
Severity of hypospadias
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
Queensland Centre for Health Data Services
 
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Created: Thu, 16 Jul 2009, 23:40:06 EST by Marisol da Silva on behalf of Faculty Of Health Sciences