Isolation and characterization of the canine NKX2-5 gene

Hyun, C., Lavulo, L., O'Leary, C. and Kim, J-T. (2006) Isolation and characterization of the canine NKX2-5 gene. Journal of Animal Breeding and Genetics, 123 3: 213-216. doi:10.1111/j.1439-0388.2006.00584.x

Author Hyun, C.
Lavulo, L.
O'Leary, C.
Kim, J-T.
Title Isolation and characterization of the canine NKX2-5 gene
Journal name Journal of Animal Breeding and Genetics   Check publisher's open access policy
ISSN 0931-2668
Publication date 2006-06
Sub-type Article (original research)
DOI 10.1111/j.1439-0388.2006.00584.x
Volume 123
Issue 3
Start page 213
End page 216
Total pages 4
Editor A. Mäki-Tanila
G. Erhardt
I. Misztal
L.R. Schaeffer
H. Simianer
J. van der Werf
Place of publication Berlin
Publisher Wiley Blackwell
Language eng
Subject 070706 Veterinary Medicine
Abstract We report the first isolation and characterization of the canine NKX2-5 gene. This canine homologue has high homology in genomic structure and functional domains to other NKX2-5 across a number of different species. Given the critical role of NKX2-5 in cardiac morphogenesis as seen in human and mouse studies of congenital heart defects, the availability of the canine NKX2-5 provides a good starting point for identifying mutations that may be responsible for certain forms of canine congenital heart defects.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Veterinary Science Publications
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Created: Tue, 28 Apr 2009, 11:48:41 EST by Maria Campbell on behalf of School of Veterinary Science