Antigens for cancer immunotherapy

Neller, Michelle A., Lopez, J. Alejandro and Schmidt, Christopher W. (2008) Antigens for cancer immunotherapy. Seminars in Immunology, 20 5: 286-295. doi:10.1016/j.smim.2008.09.006

Author Neller, Michelle A.
Lopez, J. Alejandro
Schmidt, Christopher W.
Title Antigens for cancer immunotherapy
Journal name Seminars in Immunology   Check publisher's open access policy
ISSN 1044-5323
Publication date 2008-10
Year available 2008
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.smim.2008.09.006
Open Access Status
Volume 20
Issue 5
Start page 286
End page 295
Total pages 9
Place of publication United Kingdom
Publisher Academic Press
Collection year 2008
Language eng
Subject 920102 Cancer and Related Disorders
110709 Tumour Immunology
Abstract Progress in tumor immunology has not been translated to effective immunotherapies for cancer. Most of the current effort in basic and clinical research concentrates on generating effective immune responses against model or well characterized antigens, yet vaccines targeting defined antigens have been less clinically successful than those based on whole tumor cells or their extracts. This review considers characteristics of proteins that determine how effectively they might serve as targets of immune control, and how different sources of antigens have fared in clinical trials.
Keyword Cancer
Clinical trial
Q-Index Code C1
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 65 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 16 Apr 2009, 14:05:53 EST by Sarah Elliott on behalf of Royal Brisbane Clinical School