The evaluation of a clinical scar scale for porcine burn scars

Wang, Xue-Qing, Kravchuk, Olena, Liu, Pei-Yun, Kempf, Margit, Boogaard, Carolina V. D., Lau, Peter, Cuttle, Leila, Mill, Julie and Kimble, Roy M. (2009) The evaluation of a clinical scar scale for porcine burn scars. Burns, 35 4: 538-546. doi:10.1016/j.burns.2008.10.005

Author Wang, Xue-Qing
Kravchuk, Olena
Liu, Pei-Yun
Kempf, Margit
Boogaard, Carolina V. D.
Lau, Peter
Cuttle, Leila
Mill, Julie
Kimble, Roy M.
Title The evaluation of a clinical scar scale for porcine burn scars
Journal name Burns   Check publisher's open access policy
ISSN 1879-1409
Publication date 2009-06
Sub-type Article (original research)
DOI 10.1016/j.burns.2008.10.005
Volume 35
Issue 4
Start page 538
End page 546
Total pages 8
Editor Steven Eric Wolf
Place of publication USA
Publisher Elseiver
Collection year 2010
Language eng
Subject 321000 Clinical Sciences
9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
Abstract This study describes the evaluation of a clinical scar scale for our porcine burn scars, which includes scar cosmetic outcome, colour, height and hair, supplemented with reference porcine scar photographs representing each scar outcome and scar colour scores. A total of 72 porcine burn scars at week 6 after burn were rated in vivo and/or on photographs. Good agreements were achieved for both intra-rater reliability (correlation is 0.86-0.98) and inter-rater reliability (ICC=80-85%). The results showed statistically significant correlations for each pair in this clinical scar scale (p<0.01), with the best correlation found between scar cosmetic outcome and scar colour. A multivariate principle components analysis revealed that this clinical scar assessment was highly correlated with scar histology, wound size, and re-epithelialisation data (p<0.001). More severe scars are clinically characterised by darker purple colouration, more elevation, no presence of hair, histologically by thicker scar tissue, thinner remaining normal dermis, are more likely to have worse contraction, and slower re-epithelialisation. This study demonstrates that our clinical scar scale is a reliable, independent and valuable tool for assessing porcine burn outcome and truthfully reflects scar appearance and function. To our knowledge, this is the first study demonstrating a high correlation between clinical scar assessment and scar histology, wound contraction and re-epithelialisation data on porcine burn scars. We believe that the successful use of porcine scar scales is invaluable for assessing potential human burn treatments.
Keyword Burns paediatrics
Q-Index Code C1
Q-Index Status Confirmed Code
Additional Notes Accepted in October 2008, Copyright of 2008, published in 2009

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Created: Tue, 14 Apr 2009, 15:40:50 EST